Top 7 in cell biology

A snapshot of the most highly ranked articles in cell biology and related areas, from Faculty of 1000

Written byJef Akst

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Scanning electron micrographs of B. subtilisIMAGE: COURTESY OF THE BEN-YEHUDA LABORATORY

1. Cytokines, infection blockers

Patients infected by Candida albicans -- the causative agent of chronic mucocutaneous candidiasis disease (CMCD), an infection of the oral and genital mucosae, skin, and nails -- and possibly Staphylococcus aureus, often have mutations in genes encoding interleukin-17 receptor A (IL-17RA) and IL-17F, suggesting an essential role of these cytokines in protecting against such infections.

A. Puel et al., "Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity," Science, 332:65-8, 2011. Evaluated by Dan Conrad, Virginia Commonwealth Univ; Jay Kolls, LSU Health Sciences Cen; Klaus Ley, La Jolla Inst for Allergy & Immunology; Sarah Gaffen, Univ Pitt; Joshua Milner, National Inst of Allergy and Infectious Diseases. Free F1000 evaluation

2. AMPK structure revealed

Researchers detail the crystal structure of ...

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Meet the Author

Jef Akst
Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.
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