Zika Vaccine Shows Promise in Early Clinical Trial

In humans, the DNA vaccine elicited the production of antibodies, which then protected mice from Zika infection.

Written byAshley P. Taylor
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

WIKIMEDIA, NIAIDA DNA vaccine against Zika virus has shown promising results in an early human trial. The results appeared yesterday (October 4) in the New England Journal of Medicine.

“Zika virus continues to be a threat to people living in the Americas and the Caribbean,” lead author Pablo Tebas, a professor of infectious diseases at the University of Pennsylvania, says in a release. “With these new results, we are one step closer to hopefully finding a way to prevent infection, which can cause serious birth defects and developmental delays in babies born to women who are infected with Zika.”

The vaccine, developed by Inovio Pharmaceuticals and GeneOne Life Science, is composed of a ring of DNA (a plasmid) containing the genetic instructions for producing Zika virus antigens. In the study, 40 study participants received three doses of the vaccine through injections under the skin. Patients were then exposed to a device that sends out ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

Share
December digest cover image of a wooden sculpture comprised of multiple wooden neurons that form a seahorse.
December 2025, Issue 1

Wooden Neurons: An Artistic Vision of the Brain

A neurobiologist, who loves the morphology of cells, turns these shapes into works of art made from wood.

View this Issue
Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Merck
Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

MilliporeSigma purple logo
Human iPSC-derived Models for Brain Disease Research

Human iPSC-derived Models for Neurodegenerative Disease Research

Fujifilm
Abstract wireframe sphere with colorful dots and connecting lines representing the complex cellular and molecular interactions within the tumor microenvironment.

Exploring the Inflammatory Tumor Microenvironment 

Cellecta logo

Products

brandtech logo

BRANDTECH® Scientific Announces Strategic Partnership with Copia Scientific to Strengthen Sales and Service of the BRAND® Liquid Handling Station (LHS) 

Top Innovations 2026 Contest Image

Enter Our 2026 Top Innovations Contest

Biotium Logo

Biotium Expands Tyramide Signal Amplification Portfolio with Brighter and More Stable Dyes for Enhanced Spatial Imaging

Labvantage Logo

LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS