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Contrary to long-standing assumptions, human egg cells stay pristine for decades not by ramping up waste disposal, but by dialing it down.

Despite sharing DNA sequences, monozygotic twins are epigenetically distinct and express different genes, offering a model to better understand diseases.

Scientists identified a nuclear mechanism that distinguishes chronic inflammation from acute inflammation in mice.

A neuronal mechanism pumps the brakes on pain, but failure of these brakes can cause long-lasting pain. The discovery could open new pain treatment paths.

Lac insects carry a yeast-like symbiont that produces a commercially important bright red pigment, revealing insights about insect-microbe symbiosis.

Investigating conserved signaling pathways in different cell types shows that memory is not a unique property of neurons.

Human organs-on-chips and organoids offer new alternatives to animals for drug development, but there is still a long way to go.

Zebrafish hair cells regrow via cyclin gene activity in specific cells, offering clues to future hearing restoration in humans.

A fungal pathogen has rendered the Southern corroboree frog functionally extinct. Can genomics technologies pull the species back from the brink?

A new study identified Parkinson’s disease-associated compounds from earwax, but some scientists remain skeptical.

Current CRISPR guide RNAs are designed based on European reference genomes, leading to false-negative results in cells from people with African ancestry.

In a model of chronic NAD+ depletion that mimics aging, mitochondria are revealed as a rheostat of cellular NAD+ levels.