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A deep-learning model trained on human data reveals that promoter mutations may explain a significant portion of unsolved rare diseases.

 Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can offer new treatment opportunities.

Specialized squid tissues contain refractive proteins called reflectins, which help the animal evade detection and offer potential bioengineering applications.

Engineered bacteria turned recycled plastic into paracetamol, a common analgesic, offering a fossil-free route to pharmaceuticals.

An obscure group of phages offers insights into elements of microbial warfare—and blueprints for new antibiotics.

How do animals bounce back from sleep deprivation? Scientists found a subset of neurons in the mouse thalamus that repay this “sleep debt.”

Microbiome clocks based on patterns in baboons’ gut microbes reflect demographic and socio-environmental factors, providing insights into aging.

Comparative genomics revealed genetic differences between wild and domestic animals, highlighting traits influenced by human selection.

In a competitive academic world, building bridges instead of walls may be our most powerful tool to accelerate discovery and rebuild public trust in science.

Flies that expressed an Alzheimer’s disease-related protein in their neurons showed signs of accelerated aging.

Skin cancers in horses and humans show genetic similarities, but the animals are less prone to some other cancers, offering a platform to compare disease risk.

A protein from Helicobacter pylori inhibits amyloid formation in both microbes and humans, offering new leads for antimicrobial and neurodegenerative disease therapies.