Alzheimer’s Drug Slows Symptoms, Reduces Plaques

In a clinical trial, patients on the highest injected dose had 30 percent less cognitive decline over time than people on a placebo.

kerry grens
| 2 min read

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An Alzheimer’s drug slows the rate of cognitive decline while reducing the amount of plaques in patients’ brains, according to the results of a clinical trial reported yesterday (June 25) at the Alzheimer’s Association International Conference in Chicago. Compared to participants on a placebo, those who received the highest dose of the injected medicine had a 30 percent slower progression in symptoms.

“If you could really slow decline by 30 percent for people who are still normal or very mildly impaired, that would be clinically important,” Reisa Sperling, director of the Center for Alzheimer Research and Treatment at Brigham and Women’s Hospital in Boston who was not involved in the study, tells The New York Times.

The study included more than 800 people with mild cognitive decline, and 161 received the highest of five doses, injected twice weekly for 18 months. The medicine, a monoclonal antibody called BAN2401, targets amyloid ...

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  • kerry grens

    Kerry Grens

    Kerry served as The Scientist’s news director until 2021. Before joining The Scientist in 2013, she was a stringer for Reuters Health, the senior health and science reporter at WHYY in Philadelphia, and the health and science reporter at New Hampshire Public Radio. Kerry got her start in journalism as a AAAS Mass Media fellow at KUNC in Colorado. She has a master’s in biological sciences from Stanford University and a biology degree from Loyola University Chicago.

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