Richard P. Grant
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Articles by Richard P. Grant
Down but Not Out
Richard P. Grant | | 3 min read
By Richard P. Grant Down but Not Out HIDDEN JEWEL Normal cells do not grow and divide forever. Even before they get old and die, many cells in the body are quiescent: temporarily out of the proliferative cell cycle, waiting for a signal to wake up and become active again. Cells grown in culture will also enter such a state, either because they’re too crowded or have run out of nutrients. Princeton University’s Hilary Coller recently found that s
The Great Escape
Richard P. Grant | | 1 min read
By Richard P. Grant The Great Escape 3D4Medical / Photo Researchers, Inc. The paper L.A. Knodler et al., “Dissemination of invasive Salmonella via bacterial-induced extrusion of mucosal epithelia.” PNAS, 107:17733-38, 2010. Free F1000 Evaluation The finding When the Salmonella bacterium infects eukaryotic cells, it becomes encased in membrane-bound vacuoles. How it escapes from these vacuoles and infects other cells was a mystery until now
Time and Temperature
Richard P. Grant | | 2 min read
By Richard P. Grant Time and Temperature Joseph Takahashi (An artistic representation of the SCN in black on a colorful background) The paperE. D. Buhr et al., “Temperature as a universal resetting cue for mammalian circadian oscillators,” Science, 330:379-85, 2010. Free F1000 EvaluationThe finding The body’s circadian rhythms are regulated by a “master clock” in the brain, whose tempo is set by light-dark cycles, while t
Losers Fight Back
Richard P. Grant | | 1 min read
By Richard P. Grant Losers Fight Back Dr Adam Schindler and Dr David Sherwood (Anchor cell invasion initiates uterine-vulval attachment during C. elegans larval development) The paperM. Portela et al., “Drosophila SPARC is a self-protective signal expressed by loser cells during cell competition,” Dev Cell, 19:562-73, 2010. Free F1000 EvaluationThe finding During development and aging, animal cells that have been weakened by mutation, infe
Research at recess
Richard P. Grant | | 3 min read
A gaggle of British primary school children has published important findings on bee behavior
Eau de Choice
Richard P. Grant | | 3 min read
Evolutionary biologist Jane Hurst at the University of Liverpool has found that male mice have evolved a cunning trick to distinguish themselves within the dating pool: they produce a specific protein that drives female attraction to male scent, and this molecule, called darcin, helps females remember a specific male's odor.
