COVID-19 Linked to Neural Changes

A study that examined the brains of people before and after SARS-CoV-2 infection found a decrease in brain volume and damage to olfactory areas compared with controls.

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MRI brain scans of hundreds of people in the UK taken before and after they contracted COVID-19 reveal changes that persisted months after recovery from the disease, a paper published today in Nature reports. These changes, while subtle, included tissue damage in certain brain areas, including those involved in olfaction, and a decline in overall brain size that was larger than the expected decline caused by natural aging. But experts caution that the clinical effects of these changes and whether they will persist in the long-term remain unclear.

“It is a very novel study with conclusive data,” Avindra Nath of the National Institute of Neurological Disorders and Stroke who wasn’t involved in the research tells Bloomberg. “The findings are very intriguing, with important implications for the population at large.”

The study considered 785 subjects between the ages of 51 and 81 who were each scanned twice, about three years apart. ...

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Meet the Author

  • Shawna Williams

    Shawna was an editor at The Scientist from 2017 through 2022. She holds a bachelor's degree in biochemistry from Colorado College and a graduate certificate and science communication from the University of California, Santa Cruz.
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