COVID-19 Vaccines Appear Safe During Pregnancy: Early Data

Scientists at the US CDC report no red flags in a preliminary analysis of the safety of Pfizer/BioNTech’s and Moderna’s mRNA-based immunizations among expectant mothers.

Written byChristie Wilcox, PhD
| 2 min read
pregnancy pregnant covid-19 coronavirus pandemic sars-cov-2 vaccine immunization moderna mrna pfizer/biontech

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Although transmission of the SARS-CoV-2 across the placenta is rare, pregnant people are at an increased risk for severe COVID-19, which is why many experts and scientific societies have argued that vaccination is a must during pregnancy. However, initial clinical trials excluded pregnant people, so there has been limited clinical data on this population.

Now, the first large-scale results are in, and they are encouraging. According to a study by scientists at the US Centers for Disease Control and Prevention published in the New England Journal of Medicine yesterday (April 21), there are no increased risks of severe side effects or adverse pregnancy outcomes from either the Moderna or Pfizer/BioNTech COVID-19 vaccines currently authorized for emergency use in the US.

The study examined self-reported symptoms from more than 35,000 people aged 16 to 54 who were pregnant when they received their COVID-19 vaccination and who ...

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