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The face of a young woman and the face of an old man surrounded by mechanical clocks.
Daily Gene Expression Rhythms Vary with Sex and Age: Study
By studying tissues from deceased people, a team found that women have more rhythmical gene expression and that this molecular rhythmicity decreases with age.
Daily Gene Expression Rhythms Vary with Sex and Age: Study
Daily Gene Expression Rhythms Vary with Sex and Age: Study

By studying tissues from deceased people, a team found that women have more rhythmical gene expression and that this molecular rhythmicity decreases with age.

By studying tissues from deceased people, a team found that women have more rhythmical gene expression and that this molecular rhythmicity decreases with age.

mRNA
zebrafish in an aquarium
Epigenetics May Remember Ancestors’ Mutations
Holly Barker | Dec 1, 2022 | 4 min read
Parents’ mutations, even if they’re not inherited by offspring, could affect subsequent generations through changes to epigenetic marks, a study finds.
illustration of human oocyte
Mammalian Oocytes Store mRNA in Newly Found Membraneless Structure
Alejandra Manjarrez, PhD | Oct 20, 2022 | 3 min read
The findings answer the longstanding question of where these cells hold the mRNA needed to cope with the transcriptional halt preceding meiosis.
 Learn about analyzing mRNA with direct sequence mapping 
Solutions for mRNA Direct Sequence Mapping
Thermo Fisher Scientific | 1 min read
As mRNA therapeutics gain popularity, a novel solution for their development emerges.
A photograph of Christine Guthrie and Hiten Madhani
RNA Pioneer Christine Guthrie Dies at 77
Amanda Heidt | Sep 1, 2022 | 5 min read
Guthrie established foundational concepts in the field of pre-mRNA splicing during her career at the University of California, San Francisco.
3D rendering of a scanning electron micrograph of pink malignant cancer cells against a black background
Cancers Ramp Up Overall mRNA Expression as They Progress
Dan Robitzski | Jun 14, 2022 | 4 min read
A technique for quantifying tumor mRNA production from messy tissue sample data uncovers an unexpected correlation between it and disease stage in 15 cancer types.
COVID-19 vaccine vials
COVID-19 Vaccines Induce Better Long-Term Immunity than Infection
Jennifer Zieba, PhD | 3 min read
For the first time, researchers performed a head-to head longitudinal study comparing the immune response elicited by mRNA and traditional COVID-19 vaccines to primary infections.
illustration of a large purple molecular complex with a strand of orange RNA running through it and red strand emerging from it
Study Reveals Outsize Role of mRNA Region in Tuning Expression
Sophie Fessl, PhD | Jan 27, 2022 | 3 min read
A new method helps researchers uncover the rules of ribosome recruitment in yeast.
knitted pink heart with a mended hole
CAR T Cells Mend Broken Mouse Hearts
Sophie Fessl, PhD | Jan 6, 2022 | 4 min read
Specialized immune cells generated in vivo reduce cardiac scar tissue in mice, a new study shows.
3d render illustration of Single strand ribonucleic acid.
Message in a Bottle: Developing mRNA Therapeutics
The Scientist’s Creative Services Team and Mirus Bio | 3 min read
A high efficiency, low toxicity method for direct RNA delivery into cells.
Isolated Realistic Coronavirus Covid-19 Molecule in a Biological Environment stock photo
Tweak to N Protein Makes Delta Variant More Infectious
Chloe Tenn | Nov 5, 2021 | 2 min read
Using a novel lab technique, researchers identified a mutation that allows the virus to insert more genetic material into host cells.
cartoon image showing colorful collection of syringes, coronavirus particles, and mrna to represent the vaccine development
Optogenetics and mRNA Vaccines Net Lasker Awards
Annie Melchor | Sep 24, 2021 | 2 min read
This year’s winners are Dieter Oesterhelt, Peter Hegemann, Karl Deisseroth, Drew Weissman, Katalin Karikó, and David Baltimore.
The Scientist Speaks - Thieves on the Inside: Viral Control of Host Gene Expression
Niki Spahich, PhD | 1 min read
Britt Glaunsinger discusses how viruses steal from their hosts to take over cellular processes and promote their own survival.
Woman holding a CDC COVID-19 vaccination card with both hands.
COVID-19 mRNA Vaccines Appear Effective Against Multiple Variants
Lisa Winter | May 6, 2021 | 2 min read
Data from three studies indicate that fully vaccinated patients are able to stave off severe disease from the B.1.1.7, B.1.351, and P.1 variants.
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COVID-19 Vaccines Appear Safe During Pregnancy: Early Data
Christie Wilcox, PhD | Apr 22, 2021 | 2 min read
Scientists at the US CDC report no red flags in a preliminary analysis of the safety of Pfizer/BioNTech’s and Moderna’s mRNA-based immunizations among expectant mothers.
Scientists Reverse Engineer mRNA Sequence of Moderna Vaccine
Lisa Winter | Apr 6, 2021 | 2 min read
Stanford University researchers determined the code from spare drops in discarded vials of the COVID-19 vaccine and published it on GitHub.
COVID-19, SARS-CoV-2, coronavirus, pandemic, vaccine, vaccine trials, combination, mix and match, immunity, antibodies, T cells, Pfizer, Moderna, AstraZeneca, clinical trials
COVID-19 Vaccine Combos Aim to Boost Immunity
Asher Jones | Mar 9, 2021 | 6 min read
Mix-and-match shots could simplify vaccine rollout and stimulate more-robust immune responses. Ongoing clinical trials will soon give answers.
2021 life science predictions innovations biotech mrna single-cell sequencing diagnostics
Experts Predict the Hottest Life Science Tech in 2021 and Beyond
Bob Grant | Feb 1, 2021 | 7 min read
Last year’s Top 10 Innovations judges look into their crystal balls.
How RNAs Called SINEUPs Upregulate Translation
Catherine Offord | Jan 1, 2021 | 2 min read
The recently discovered long noncoding RNAs seem to boost the production of specific proteins in the cell by interacting with RNA-binding proteins, researchers find.
a mockup of an at-home COVID-19 test in development
Top Technical Advances of 2020
Shawna Williams | Dec 18, 2020 | 3 min read
The pandemic spurred innovation in a variety of ways, from CRISPR-based diagnostics to cell biology benchwork at home.
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