mRNA

Beyond his achievements in academia, he also cofounded three pharmaceutical companies and filed 15 patents related to cancer therapeutics. 

By studying tissues from deceased people, a team found that women have more rhythmical gene expression and that this molecular rhythmicity decreases with age.

Parents’ mutations, even if they’re not inherited by offspring, could affect subsequent generations through changes to epigenetic marks, a study finds.

The findings answer the longstanding question of where these cells hold the mRNA needed to cope with the transcriptional halt preceding meiosis.

Guthrie established foundational concepts in the field of pre-mRNA splicing during her career at the University of California, San Francisco.

For the first time, researchers performed a head-to head longitudinal study comparing the immune response elicited by mRNA and traditional COVID-19 vaccines to primary infections.

A technique for quantifying tumor mRNA production from messy tissue sample data uncovers an unexpected correlation between it and disease stage in 15 cancer types.

A new method helps researchers uncover the rules of ribosome recruitment in yeast.

Specialized immune cells generated in vivo reduce cardiac scar tissue in mice, a new study shows.

Using a novel lab technique, researchers identified a mutation that allows the virus to insert more genetic material into host cells.

This year’s winners are Dieter Oesterhelt, Peter Hegemann, Karl Deisseroth, Drew Weissman, Katalin Karikó, and David Baltimore.

Data from three studies indicate that fully vaccinated patients are able to stave off severe disease from the B.1.1.7, B.1.351, and P.1 variants.

Scientists at the US CDC report no red flags in a preliminary analysis of the safety of Pfizer/BioNTech’s and Moderna’s mRNA-based immunizations among expectant mothers.

Stanford University researchers determined the code from spare drops in discarded vials of the COVID-19 vaccine and published it on GitHub.

Mix-and-match shots could simplify vaccine rollout and stimulate more-robust immune responses. Ongoing clinical trials will soon give answers.