mRNA

Specialized immune cells generated in vivo reduce cardiac scar tissue in mice, a new study shows.

Using a novel lab technique, researchers identified a mutation that allows the virus to insert more genetic material into host cells.

This year’s winners are Dieter Oesterhelt, Peter Hegemann, Karl Deisseroth, Drew Weissman, Katalin Karikó, and David Baltimore.

Data from three studies indicate that fully vaccinated patients are able to stave off severe disease from the B.1.1.7, B.1.351, and P.1 variants.

Scientists at the US CDC report no red flags in a preliminary analysis of the safety of Pfizer/BioNTech’s and Moderna’s mRNA-based immunizations among expectant mothers.

Stanford University researchers determined the code from spare drops in discarded vials of the COVID-19 vaccine and published it on GitHub.

Mix-and-match shots could simplify vaccine rollout and stimulate more-robust immune responses. Ongoing clinical trials will soon give answers.

Last year’s Top 10 Innovations judges look into their crystal balls.

The recently discovered long noncoding RNAs seem to boost the production of specific proteins in the cell by interacting with RNA-binding proteins, researchers find.

The pandemic spurred innovation in a variety of ways, from CRISPR-based diagnostics to cell biology benchwork at home.

Long before Moderna’s and Pfizer’s COVID-19 shots, scientists had been considering the use of genetically encoded vaccines in the fight against infectious diseases, cancer, and more.

The results mark the second experimental COVID-19 vaccine to show high efficacy, but the study is not complete and the data have not been peer reviewed.

Researchers detail how viral proteins interact with host RNA to disrupt the cell’s ability to fight back against infection.

The way in which mRNA transcripts are cut can influence the elasticity of the organ.

It’s now clear that gene transcripts can be constructed in various ways, yet many questions remain about the process.

An enzyme blocker is highly effective at treating intestinal parasitic infection in mice.

DNA microscopy pinpoints the locations of transcripts by laying a grid of tags over the molecules and labeling each connection.

One of the foremost molecular biologists of the 20th century, the Nobel laureate established C. elegans as a model organism, mapping its genes and development.