Environmental Impact

Research in behavioral epigenetics is seeking evidence that links experience to biochemistry to gene expression and back out again.

Written byDavid Berreby
| 11 min read

Register for free to listen to this article
Listen with Speechify
0:00
11:00
Share

JASPER JAMES / GETTYIMAGES

In the late 1970s, when Hans Reul was a student running gels on the rich soup of proteins around DNA and RNA, he found himself wondering about the function of those nongenetic molecules in his samples. “I asked my supervisor, ‘What are those proteins down there?’ he recalls. “And he said, ‘Well, they’re histone molecules. We have no clue what they’re doing. They sit in the nucleus and do something with the DNA.”

At the time, for researchers chasing links between genes and behavior, all the tools and all the promise seemed to focus on two molecules, DNA and RNA. So did depictions in the popular media of the links between genes and personality. It was the era when Nobelist Walter Gilbert, extolling the Human ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies