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Exome Sequencing Helps Crack Rare Disease Diagnosis
Amanda B. Keener | May 1, 2018
Clinical analyses of patients’ gene sequences are helping to provide answers where none were available before.
New Techniques Detail Embryos’ First Hours and Days
Jef Akst | Dec 1, 2017
New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.
Infographic: How Embryos Take Control of Their Own Development
Jef Akst | Nov 30, 2017
The switch from maternal factors involves dynamic reprogramming of the zygotic genome.
The Role of DNA Base Modifications
Skirmantas Kriaucionis | Sep 1, 2017
Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.
Infographic: The Various Forms of Methylated DNA
Skirmantas Kriaucionis | Aug 31, 2017
To expand the basic nucleotide alphabet, many species modify their DNA with epigenetic marks.
Plants’ Epigenetic Secrets
Jef Akst | Feb 1, 2017
Unlike animals, plants stably pass on their DNA methylomes from one generation to the next. The resulting gene silencing likely hides an abundance of phenotypic variation.
Infographic: Plant Methylation Basics
Jef Akst | Jan 31, 2017
Multiple molecular mechanisms keep plant DNA methylation in order.
Exploring the Epigenetics of Ethnicity
Anna Azvolinsky | Jan 10, 2017
Researchers attempt to estimate how much of the human genome’s methylation patterns can be attributed to genetic ancestry.
Anna Azvolinsky | Jan 1, 2017
After initially discovering that DNA methylation represses transcription, Howard Cedar continues to explore how the epigenetic mark regulates gene expression.
Transgenerational Epigenetics Prepares Plants for Drought
Ben Andrew Henry | Jan 1, 2017
Plants grown in dry soil produce offspring that are hardier in drought conditions, and DNA methylation appears responsible.