First US Outbreak of COVID-19 Seeded in Mid-February: Preprint

A modeling study counters initial interpretations that the cluster began with someone who flew to Seattle in mid-January.

Written byKerry Grens
| 2 min read
seattle coronavirus outbreak pandemic covid-19 sars-cov-2 genome wa1 washington transmission wuhan china phylogeny virology

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

ABOVE: © ISTOCK.COM, 400TMAX

An outbreak of coronavirus infections in Washington State that began at the end of February was likely sparked by a traveler who entered the state in mid-February, rather than by an infected person who flew from Wuhan, China, to Seattle in mid-January, as was previously thought. That’s the conclusion of a preprint posted on bioRxiv May 23 that modeled various transmission scenarios based on the genomes of viral samples collected from patients in Washington State and elsewhere.

The study confirms “a lot of what we were starting to suspect from the epidemiological data, that there were some early introductions in the West Coast that did not spark sustained transmission,” Northeastern University’s Samuel Scarpino, who was not involved in the work, tells STAT.

Initial studies by Trevor Bedford, who studies pathogen evolution at the Fred Hutchinson Cancer Research Center and the University of Washington, indicated that the ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • kerry grens

    Kerry served as The Scientist’s news director until 2021. Before joining The Scientist in 2013, she was a stringer for Reuters Health, the senior health and science reporter at WHYY in Philadelphia, and the health and science reporter at New Hampshire Public Radio. Kerry got her start in journalism as a AAAS Mass Media fellow at KUNC in Colorado. She has a master’s in biological sciences from Stanford University and a biology degree from Loyola University Chicago.

    View Full Profile
Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies