Genome Digest

What researchers are learning as they sequence, map, and decode species’ genomes

Written byDan Cossins
| 6 min read

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Model of a coelacanth in the Houston Museum of Natural ScienceWIKIMEDIA, DADEROT

Species: African coelacanth (Latimeria chalumnae)
Genome size: ~2.86 billion base pairs

The African coelacanth (Latimeria chalumnae) was thought to have gone extinct around 70 million years ago until a fisherman caught one off the coast of the South Africa in 1938. The fish looked so much like its fossilized ancestors of 300 million years ago that it was labeled a “living fossil.” That’s a controversial term, as looks can be deceiving but parts of the coelacanth’s genome do appear to be changing more slowly than those of other vertebrates.

Having acquired DNA from a rare fresh-caught specimen, an international team of researchers sequenced the whole coelacanth genome, revealing surprisingly little change in the fish’s protein-coding genes, as compared with a chicken and several mammals. The ...

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