How Some Vaccines Protect Against More than Their Targets

As researchers test existing vaccines for nonspecific protection against COVID-19, immunologists are working to understand how some inoculations protect against pathogens they weren’t designed to fend off.

Written byShawna Williams
| 20 min read

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As a physician-researcher specializing in infections in newborns, Tobi Kollmann is laser focused on how to stop babies from dying. While mortality for kids under five years old has dropped substantially in recent decades, he says, there has been little improvement in the rate of deaths in the first week of life. Indeed, of the 5.2 million children under 5 years old the World Health Organization estimates died last year of preventable or treatable causes, nearly half—2.4 million—died before reaching four weeks of age, and most newborn deaths occurred in the first week after birth. Having spent time in African countries where neonatal mortality is common and witnessed the frustration of colleagues there with their limited options for preventing it, Kollmann, now at the Telethon Kids Institute in Perth, Australia, says he wanted to find solutions that could be implemented immediately.

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Meet the Author

  • Shawna was an editor at The Scientist from 2017 through 2022. She holds a bachelor’s degree in biochemistry from Colorado College and a graduate certificate in science communication from the University of California, Santa Cruz. Previously, she worked as a freelance editor and writer, and in the communications offices of several academic research institutions. As news director, Shawna assigned and edited news, opinion, and in-depth feature articles for the website on all aspects of the life sciences. She is based in central Washington State, and is a member of the Northwest Science Writers Association and the National Association of Science Writers.

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