Human Fetuses Can Contract SARS-CoV-2, but It’s Rare

Compared with Zika and cytomegalovirus, the virus that causes COVID-19 appears to have a harder time penetrating the placenta and moving to a woman’s unborn baby.

Written byAshley Yeager
| 11 min read

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Drucilla Roberts and Vanda Torous stared at the placental tissue of two babies—fraternal twins—and were stunned by what they saw. The twins had shared the same womb and obviously the same mother, who’d tested positive for SARS-CoV-2 during delivery, yet the babies’ individual placentas looked very different, Roberts recalls. The tissue of one of the placentas was severely inflamed, riddled with immune cells. The other one looked healthy. When Roberts and Torous, who are both pathologists at Massachusetts General Hospital in Boston, ordered tests of the placental tissue for markers of SARS-CoV-2, the inflammation-riddled organ appeared to be heavily infected with the virus, while the other one had relatively little viral RNA.

Neither twin tested positive for the novel coronavirus after birth, Roberts tells The Scientist. “The babies are fine.” The fact that one placenta was heavily infected by the virus and severely ...

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Meet the Author

  • Ashley started at The Scientist in 2018. Before joining the staff, she worked as a freelance editor and writer, a writer at the Simons Foundation, and a web producer at Science News, among other positions. She holds a bachelor’s degree in journalism from the University of Tennessee, Knoxville, and a master’s degree in science writing from MIT. Ashley edits the Scientist to Watch and Profile sections of the magazine and writes news, features, and other stories for both online and print.

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Published In

January 2021

Expecting and Infected

What science is revealing about COVID-19 in mothers to be

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