Human Fetuses Can Contract SARS-CoV-2, but It’s Rare

Compared with Zika and cytomegalovirus, the virus that causes COVID-19 appears to have a harder time penetrating the placenta and moving to a woman’s unborn baby.

Written byAshley Yeager
| 11 min read

Register for free to listen to this article
Listen with Speechify
0:00
11:00
Share

ABOVE: MODIFIED FROM © ISTOCK.COM, ELENA MAKEEVA

Drucilla Roberts and Vanda Torous stared at the placental tissue of two babies—fraternal twins—and were stunned by what they saw. The twins had shared the same womb and obviously the same mother, who’d tested positive for SARS-CoV-2 during delivery, yet the babies’ individual placentas looked very different, Roberts recalls. The tissue of one of the placentas was severely inflamed, riddled with immune cells. The other one looked healthy. When Roberts and Torous, who are both pathologists at Massachusetts General Hospital in Boston, ordered tests of the placental tissue for markers of SARS-CoV-2, the inflammation-riddled organ appeared to be heavily infected with the virus, while the other one had relatively little viral RNA.

Neither twin tested positive for the novel coronavirus after birth, Roberts tells The Scientist. “The babies are fine.” The fact that one placenta was heavily infected by the virus and severely ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • Ashley started at The Scientist in 2018. Before joining the staff, she worked as a freelance editor and writer, a writer at the Simons Foundation, and a web producer at Science News, among other positions. She holds a bachelor’s degree in journalism from the University of Tennessee, Knoxville, and a master’s degree in science writing from MIT. Ashley edits the Scientist to Watch and Profile sections of the magazine and writes news, features, and other stories for both online and print.

    View Full Profile

Published In

January 2021

Expecting and Infected

What science is revealing about COVID-19 in mothers to be

Share
July Digest 2025
July 2025, Issue 1

What Causes an Earworm?

Memory-enhancing neural networks may also drive involuntary musical loops in the brain.

View this Issue
Genome Modeling and Design: From the Molecular to Genome Scale

Genome Modeling and Design: From the Molecular to Genome Scale

Twist Bio 
Screening 3D Brain Cell Cultures for Drug Discovery

Screening 3D Brain Cell Cultures for Drug Discovery

DNA and pills, conceptual illustration of the relationship between genetics and therapeutic development

Multiplexing PCR Technologies for Biopharmaceutical Research

Thermo Fisher Logo
Discover how to streamline tumor-infiltrating lymphocyte production.

Producing Tumor-infiltrating Lymphocyte Therapeutics

cytiva logo

Products

waters-logo

Waters and BD's Biosciences & Diagnostic Solutions Business to Combine, Creating a Life Science and Diagnostics Leader Focused on Regulated, High-Volume Testing

zymo-research-logo

Zymo Research Partners with Harvard University to Bring the BioFestival to Cambridge, Empowering World-class Research

10x-genomics-logo

10x Genomics and A*STAR Genome Institute of Singapore Launch TISHUMAP Study to Advance AI-Driven Drug Target Discovery

The Scientist Placeholder Image

Sino Biological Sets New Industry Standard with ProPure Endotoxin-Free Proteins made in the USA