Immunity to SARS-CoV-2 Lasts at Least Six Months, Data Show

Half a year after infection, people who had recovered from COVID-19 had robust antibodies, along with traces of the virus in their gut, which may drive long-lasting immunity.

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ABOVE: Recovered COVID-19 patients can harbor SARS-CoV-2 (green) in the lining of their intestines months after infection. The residual viral traces might shape the immune response to the virus.
C. GAEBLER ET AL, BIOARXIV, 2020

Immunity to the virus that causes COVID-19 lasts at least six months and might last much longer, according to a preprint posted November 5 on bioRxiv.

Among 87 individuals who had COVID-19, antibodies to SARS-CoV-2 dwindled after six months but were still detectable, the study’s authors found. A closer look at the samples of six of those patients revealed that the antibodies that remained six months after infection were, on average, more potent in neutralizing the virus than were antibodies generated only about a month after infection. And levels of the memory immune cells that make those more-potent antibodies did not drop off with time, the researchers report.

“This is fantastic news,” says immunologist Ziv Shulman ...

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Meet the Author

  • Ashley Yeager

    Ashley started at The Scientist in 2018. Before joining the staff, she worked as a freelance editor and writer, a writer at the Simons Foundation, and a web producer at Science News, among other positions. She holds a bachelor’s degree in journalism from the University of Tennessee, Knoxville, and a master’s degree in science writing from MIT. Ashley edits the Scientist to Watch and Profile sections of the magazine and writes news, features, and other stories for both online and print.

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