Indigenous Filipino Group Has Highest Known Denisovan Ancestry

Researchers found the relatively high proportion of DNA from a hominin cousin—nearly 5 percent—when they scanned more than 1,000 genomes from 118 distinct ethnic groups.

Written byAnnie Melchor
| 3 min read
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ABOVE: Self-identified Negritos from various islands of the Philippines.
OPHELIA PERSSON

Until recently, scientists thought the modern humans with the highest proportion of Denisovan ancestry lived in Papua New Guinea and Australia. According to a new study published yesterday (August 12) in Current Biology, however, an Indigenous group in the Philippines called the Ayta Magbukon have 30 to 40 percent more Denisovan DNA than these other frontrunners, for a total of nearly 5 percent of their genomes.

Denisovans were a group of archaic humans first identified from a single pinkie bone in a Siberian cave. They coexisted with modern humans and other archaic human species, such as Neanderthals, for hundreds of thousands of years, until they went extinct an estimated 30,000 to 50,000 years ago. According to Gizmodo, only Pacific Islanders and Southeast Asians have substantial Denisovan ancestry. By comparison, most people in other parts of mainland Asia have less than ...

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    Stephanie "Annie" Melchor got her PhD from the University of Virginia in 2020, studying how the immune response to the parasite Toxoplasma gondii leads to muscle wasting and tissue scarring in mice. While she is still an ardent immunology fangirl, she left the bench to become a science writer and received her master’s degree in science communication from the University of California, Santa Cruz, in 2021. You can check out more of her work here.

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