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Killifish Embryos Pause Development Without Consequence: Study

Contrary to popular thinking, the period of arrested development is an active state of maintaining muscle integrity.

Written byLisa Winter
| 3 min read

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ABOVE: Killifish embryos that go through diapause have no ill effects later in life. © CHI-KUO HU

Rather than risk being born during the dry season when conditions are not hospitable, African killifish embryos are able to arrest their development and wait to hatch until the rainy season replenishes their pond. This can occur for a length of time that exceeds the animal’s normal lifespan with no ill effects, according to a study published today (February 21) in Science.

Diapause is the biological phenomenon that allows animals, typically insects and certain fish, to effectively hit the pause button on their lifecycle to avoid extremely adverse conditions. For African turquoise killifish (Nothobranchius furzeri), this usually occurs at the embryonic stage, allowing the fish to wait until there is sufficient water to hatch.

The team found that during diapause, cells responsible for growth suspend activity and metabolism slows, but genes that code ...

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Meet the Author

  • Lisa joined The Scientist in 2017. As social media editor, some of her duties include creating content, managing interactions, and developing strategies for the brand’s social media presence. She also contributes to the News & Opinion section of the website. Lisa holds a degree in Biological Sciences with a concentration in genetics, cell, and developmental biology from Arizona State University and has worked in science communication since 2012.

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