Features
The Literature

Viral Skeleton
A newly discovered family of tubulins—members of the cytoskeleton—encoded by bacteriophages plays a role in arranging the location of DNA within virus’s bacterial host.

Microbial Awakening
Successive awakening of soil microbes drives a huge pulse of CO2 following the first rain after a dry summer.

Exit Strategy
Large RNA-protein packets use a novel mechanism to escape the cell nucleus.
Notebook

Dolled-Up Turtles
Borrowing techniques from nail and hair salons, researchers have devised a method to tag small, previously untrackable sea turtles.

Chocolate and Cheese
Taking gastronomy to the molecular level creates unprecedented flavor combos.

A Celebrated Symposium
A conference, started 10 years ago partly as a disease ecologist’s birthday party, has become one of the most valued meetings in the field.

Pneu-mummy-a
Comparing the protein profile of a 500-year-old Inca mummy to modern humans reveals an active lung infection prior to sacrifice.
Contributors

Contributors
Meet some of the people featured in the November 2012 issue of The Scientist.
Critic at Large

Little Fish in a Big Pond
Continued overfishing of forage fish such as sardines and herring can result in devastating ecological and economic outcomes.

Military Mind Wars
How neuroscience research can inform military counterintelligence tactics, and the moral responsibilities that accompany such research
Foundations

Poetry and Pictures, circa 1830
On the bicentennial of his birth, Edward Lear is celebrated for his whimsical poetry and his stunningly accurate scientific illustrations.
Scientist to Watch

Erica Larschan: Hitting Her Targets
Assistant Professor, Molecular Biology, Cell Biology, & Biochemistry Brown University, Age: 36
Profiles

The Road Less Traveled
First, Aravinda Chakravarti drew a map of how scientists might unravel the genetics of complex disease. Then he blazed the trail.
Speaking of Science

Speaking of Science
November 2012's selection of notable quotes
Bio Business

Tumor Snipers
After two headline successes, companies rush to develop “smart bomb” cancer drugs.
Lab Tools

A Guide to the Epigenome
Making sense of the data deluge

Creative Emulsification
Enhancing data collection from emulsion PCR reactions: three case studies

PCR Usage and Preferences
Quantitative real-time technology dominates the market today but digital PCR is on the rise.
Capsule Reviews

Capsule Reviews
Spillover, Answers for Aristotle, Who’s in Charge? and Science Set Free
Reading Frames

Truth and Consequences
Studying the consequences of behavior has shed light on a wide range of life-science phenomena, pathological as well as everyday.
Cover Story

Coming to Terms
New noninvasive methods of selecting the most viable embryo could revolutionize in vitro fertilization.
Modus Operandi

Timing Turnover
Two-tone fluorescent tags track the movement and life span of proteins within living cells.
Editorial

Long and Rocky Roads
From basic research to beneficial therapies