January 2018

The Science of Pain

New research on an age-old ailment

Features

Targeting Sodium Channels for Pain Relief

Glial Ties to Persistent Pain

Animal Analgesics

geography cone shell, Conus geographus, hunting at night, Lady Elliot Island, Great Barrier Reef Marine Park, South Pacific Ocean, Queensland, Australia

Novel Analgesics at a Snail’s Pace

Researchers Mine Centipede Toxins for Analgesics

Mining Spider Toxins for Analgesic Clues

Toxin from a Dangerous Fish Delicacy

Sourcing Painkillers from Scorpions’ Stings

Sea Anemone Toxin Could Treat Autoimmunity

Frog Skin Yields Potent Painkillers, but None Clinic Ready

The Black Mamba is the longest, fastest and most dangerous venomous snake of Africa.

Snake Venoms Cause and Block Pain

Reading Frames

Book Excerpt from Swearing is Good for You

Why Swearing and Pain Go Hand in Hand

Contributors

Contributors

Editorial

Prizes and Penalties

Speaking of Science

Ten-Minute Sabbatical

Freeze Frame

Caught on Camera

Notebook

What Bat Quarrels Tell Us About Vocal Learning

Sex Differences in Opioid Analgesia: A Complicated Picture

Researchers Team Up with Patients to Build a Breast Cancer Database

Mothers Are Hard-Wired to Respond Similarly to Infant Cries Across Cultures

Online First

Child Receives Transgenic Skin

Modus Operandi

3-D–Printed Ethoscopes Lower Barriers to Large-Scale Fly Behavior Studies

The Literature

Distinct Regions Drive Responses to Anxiety, Fear

Skin “Remembers” Wounds, Heals Faster the Second Time Around

Linoleic Acid Derivatives Potentially Mediate Pain and Itch in the Skin

Profiles

David Julius Probes the Molecular Mechanics of Pain

Scientist to Watch

Annina Schmid Dissects Nerve Disorders

Lab Tools

High-Throughput Epigenetics Analyses

Bio Business

The Quest for Safer Opioid Drugs

Foundations

Atlas of Mars by Giovanni Schiaparelli, made in 1888. Note that this is a South-Up map; the South Pole is on top.

Fake News: Mars Edition, circa 1877

Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

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Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

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Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina

Products

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Nuclera eProtein Discovery System installed at leading Universities in Taiwan

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BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

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Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

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