Neuron Populations Involved in Mouse Olfaction Change Over Time

Male mice exposed to females, their urine, or a chemical in their urine lost sensory neurons in their vomeronasal organs that respond to that chemical.

| 4 min read

Register for free to listen to this article
Listen with Speechify
0:00
4:00
Share

NIFTY SNIFFERS: Sensory neurons in the olfactory organs of mice are incredibly plastic.© ISTOCK.COM/JOE ZELLNER

A few years ago, Pei Sabrina Xu, then a graduate student in Timothy Holy’s lab at Washington University School of Medicine in St. Louis, was trying to design an enclosure for mice that allowed males to smell (but not interact with) females, and vice versa. The animals were usually kept in separate cages, but Xu wanted them to be exposed directly to chemicals released by the other sex.

She brought up the project at a lab meeting, and one of her colleagues suggested that she create a stacked enclosure. She could house the females in the top half and the males in the lower, or vice versa, allowing the urine from the upper deck to drip down into the lower layer. Xu headed to the ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Keywords

Meet the Author

  • Jef Akst

    Jef Akst was managing editor of The Scientist, where she started as an intern in 2009 after receiving a master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses.

Published In

November 2016

Nimble Neurons

The remarkable adaptability of the nervous system

Share
May digest 2025 cover
May 2025, Issue 1

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

View this Issue
iStock

TaqMan Probe & Assays: Unveil What's Possible Together

Thermo Fisher Logo
Meet Aunty and Tackle Protein Stability Questions in Research and Development

Meet Aunty and Tackle Protein Stability Questions in Research and Development

Unchained Labs
Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Bio-Rad
How technology makes PCR instruments easier to use.

Making Real-Time PCR More Straightforward

Thermo Fisher Logo

Products

fujirebio-square-logo

Fujirebio Receives Marketing Clearance for Lumipulse® G pTau 217/ β-Amyloid 1-42 Plasma Ratio In-Vitro Diagnostic Test

The Scientist Placeholder Image

Biotium Launches New Phalloidin Conjugates with Extended F-actin Staining Stability for Greater Imaging Flexibility

Leica Microsystems Logo

Latest AI software simplifies image analysis and speeds up insights for scientists

BioSkryb Genomics Logo

BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours