New Kind of Cellular Suicide

Researchers identify a gene that drives a type of cellular suicide that differs from the more commonly observed apoptosis phenomenon.

Written byJef Akst
| 1 min read

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WIKIMEDIA COMMONS, NATIONAL HUMAN GENOME RESEARCH INSTITUTE

Apoptosis isn’t the only way to kill a cell, according to new research published today (February 23) in Science, in which researchers identified a gene underlying a new cell death pathway.

Cell death is an important part of life. It is critical for shaping developing organs and eliminating infected or dying cells, among other functions. The most well studied mechanism of cell death is apoptosis, which can be found in widespread organisms and tissue systems. But mice have been known to survive without key apoptosis genes, and certain cells of Caenorhabditis elegans worms undergo a death process that doesn’t require the caspases and other known apoptosis genes, suggesting some other cell death process is at work.

Taking a closer look at the linker cells of ...

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  • Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.

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