Newer Vaccine Technologies Deployed to Develop COVID-19 Shot

Researchers look to messenger RNA encased in nanoparticles, DNA plasmids, molecular clamps, and other approaches as they rush to design a vaccine against the new coronavirus.

Written byAbby Olena, PhD
| 6 min read
coronavirus vaccine covid-19 sars-cov-2

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The Chinese Center for Disease Control and Prevention reported on February 20 that the novel coronavirus illness known as COVID-19 has now infected nearly 75,000 people and that the number of fatalities in China has doubled since February 11, from 1,016 to 2,118. Amid uncertainty about the course of the outbreak, researchers in academia and industry are using a variety of approaches in their urgency to develop a vaccine that will work to contain the virus.

When COVID-19 came on the scene, David Weiner, the director of the Vaccine & Immunotherapy Center at the Wistar Institute in Philadelphia, and his group were already part of a project led by pharmaceutical company Inovio to develop a DNA-based vaccine for Middle East Respiratory Syndrome (MERS), which is caused by a coronavirus. The Coalition for Epidemic Preparedness Innovation (CEPI), whose mission is to accelerate development of vaccines in epidemic ...

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Meet the Author

  • abby olena

    As a freelancer for The Scientist, Abby reports on new developments in life science for the website. She has a PhD from Vanderbilt University and got her start in science journalism as the Chicago Tribune’s AAAS Mass Media Fellow in 2013. Following a stint as an intern for The Scientist, Abby was a postdoc in science communication at Duke University, where she developed and taught courses to help scientists share their research. In addition to her work as a science journalist, she leads science writing and communication workshops and co-produces a conversational podcast. She is based in Alabama.  

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