No Reduction in COVID-19 Hospitalizations, Deaths with Ivermectin

The ACTIV-6 trial reports that people who took the drug for three days may have spent slightly less time feeling unwell with SARS-CoV-2, but fails to find differences in disease progression between the treatment and placebo groups.

Written byCatherine Offord
| 2 min read
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Alarge study investigating potential repurposed treatments for COVID-19 has found no benefit for ivermectin in reducing a person’s risk of being hospitalized or dying from the disease, according to a preprint posted by the researchers on medRxiv yesterday (June 12). The randomized placebo-controlled trial included more than 1,500 people, and adds to a growing body of research suggesting the antiparasitic drug is unlikely to be effective at staving off disease progression.

“Overall, most people improved their symptoms whether they took ivermectin or not,” study coauthor Adrian Hernandez, executive director of the Duke Clinical Research Institute, says in a press statement. He adds that “there does not appear to be a role for ivermectin outside of a clinical trial setting, especially considering other available options with proven reduction in hospitalizations and death.”

The trial was conducted as part of ACTIV-6, a multi-arm study funded by the National Institutes of Health (NIH) ...

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Meet the Author

  • After undergraduate research with spiders at the University of Oxford and graduate research with ants at Princeton University, Catherine left arthropods and academia to become a science journalist. She has worked in various guises at The Scientist since 2016. As Senior Editor, she wrote articles for the online and print publications, and edited the magazine’s Notebook, Careers, and Bio Business sections. She reports on subjects ranging from cellular and molecular biology to research misconduct and science policy. Find more of her work at her website.

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