Plant RNA Paper Questioned

Remarkable findings of ingested plant miRNA in animal liver and blood draw speculation about the study’s validity.

Written byEmily Willingham
| 4 min read

Register for free to listen to this article
Listen with Speechify
0:00
4:00
Share

Paddy fields in the northeast of ChinaWIKIMEDIA COMMONS, CHARLIE FONG

When the news broke last September about a study identifying small RNAs from ingested plants in animals, the focus shifted unexpectedly and quickly to potential implications for genetically modified (GM) food safety. But some experts in the field of RNA interference (RNAi) feared that the GM-related concerns were misplaced, and that there were more fundamental issues with the research.

The research team, led by Chen-Yu Zhang of Nanjing University, China, reported finding small RNA molecules from ingested rice and other plants in the bloodstream of both mice and humans and in mice livers. One of these RNAs from rice, they found, could inhibit a mouse protein that usually aids in removal of LDL or “bad” cholesterol from the blood.

The controversy surrounding the results started ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

Thermo Fisher Logo

Products

Brandtech Logo

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

Biotium Logo

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Fisher Logo
Abstract background with red and blue laser lights

VANTAstar Flexible microplate reader with simplified workflows

BMG LABTECH