ABOVE: Duke neurosurgeon Allan Friedman biopsies a glioblastoma tumor. SHAWN ROCCO/DUKE HEALTH
A genetically modified poliovirus given to patients with recurrent glioblastoma—an advanced form of brain cancer—appears to lengthen survival times, researchers reported today (June 26) in the New England Journal of Medicine. The team also presented the results today at the International Conference on Brain Tumor Research and Therapy in Norway.
“Glioblastoma remains a lethal and devastating disease, despite advances in surgical and radiation therapies, as well as new chemotherapy and targeted agents,” study coauthor Darell Bigner, emeritus director of the Preston Robert Tisch Brain Tumor Center at Duke University, says in a statement. Doctors need different approaches to treat the disease, he notes. “With the survival rates in this early phase of the poliovirus therapy, we are encouraged and eager to continue with the additional studies that are already underway or planned.”
The prognosis for patients with glioblastoma ...
