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This is DishBrain, an in vitro system that combines human brain cells with artificial intelligence technology, which researchers at Australian biotech Cortical Labs recently trained to play the classic 1972 Atari video game Pong. Fluorescent markers show axons in green, neuron bodies in purple, dendrites in red, and all other cells in blue. Where multiple markers are present, colors are merged and typically appear as yellow or pink. Posted: October 12, 2022

Caught on Camera

The Scientist Staff | Dec 12, 2022 | 4 min read

See some of the coolest images recently featured by The Scientist.

outline of a brain slice with white patch surrounded by teal

Astrocytes Feed Glioblastoma, Promoting Tumor Growth: Mouse Study

Patience Asanga | Oct 5, 2022 | 3 min read

Starving glioblastoma tumors of the cholesterol made by astrocytes could suppress brain cancer progression.

Building Cancer Models with Creative Collaborators

Deanna MacNeil, PhD | 1 min read

Jennifer Munson shares how teamwork and collaboration have fostered her research at the intersection of creativity and clinical discovery.

black-and-white brain scan showing tumor

Glioblastoma Cells Imitate Immature Neurons to Invade the Brain

Sophie Fessl, PhD | Aug 5, 2022 | 3 min read

Neuron-like glioblastoma cells are the pioneers of deadly tumors’ spread through the brain, contributing to their devastating invasiveness, a study in mice finds.

Molecular Imaging Pioneer, Sanjiv “Sam” Gambhir, Dies at 57

Lisa Winter | Jul 28, 2020 | 3 min read

The Stanford Medical School professor’s research aided the development of positron emission tomography (PET) reporters to identify disease.

Learn about innovations in tissue regeneration

Stem Cell Engineering for Tissue Regeneration

The Scientist’s Creative Services Team | 1 min read

Innovative strategies drive stem cell repair of organ damage.

Zika as Cancer Buster?

Amy Schleunes | Apr 1, 2020 | 2 min read

By infecting glioblastoma cells but not healthy brain tissue, some form of the virus could serve a therapeutic purpose.

CAR T Cell Adds Scorpion Venom to Tackle Tumor Heterogeneity

Amy Schleunes | Mar 24, 2020 | 5 min read

A newly engineered CAR T cell that incorporates a peptide isolated from the venom of the deathstalker scorpion has broad brain tumor–binding capabilities that will be investigated in an upcoming clinical trial.

A New Model with Fully Functioning Blood Vessels Mimics Brain Cancer

Roni Dengler, PhD | 2 min read

A newly developed platform may one day replace cell culture and animal models to personalize cancer treatment.

Air Pollution Tied to Brain Cancer: Study

Emily Makowski | Nov 13, 2019 | 2 min read

Inhaling combustion-produced particles may lead to the development of brain tumors.

Immune-Activating Gene Therapy for Glioblastoma

Ruth Williams | Aug 14, 2019 | 3 min read

The results of an early trial in 31 brain cancer patients finds immune activity boosted in the tumor, and possibly longer survival.

The Structure and Functions of the p53 Pathway: Information Acquisition, Redundancy, and Connectivity

The Scientist’s Creative Services Team | 1 min read

Arnold Levine will discuss his discovery of p53 and the evolution of the field since then, and Jon Chen will discuss the use of single-cell phosphoproteomics in identifying changes in key signaling networks, including p53.

Glioblastoma on a Chip

Jef Akst | Jul 15, 2019 | 3 min read

Researchers use 3-D printing technology to construct a brain cancer model that accurately recapitulated in vivo biology and predicted patient drug responses.

Infographic: A 3-D Printed Brain Tumor

Jef Akst | Jul 15, 2019 | 1 min read

How researchers create a glioblastoma on a chip that can predict patients’ response to treatments

Why Is Cancer More Common in Men Than in Women?

Jef Akst | Apr 1, 2019 | 4 min read

The molecular processes that lead males to be more susceptible to the disease are only beginning to come to light.

The Next Frontier of CAR T-Cell Therapy: Solid Tumors

Kerry Grens | Apr 1, 2019 | 10+ min read

The technology has wowed the field by all but obliterating some patients’ blood cancers, but solid malignancies present new challenges.

Traitorous Tumor Cells Kill Their Own Kind

Ruth Williams | Jul 11, 2018 | 3 min read

Researchers plan to turn cancer cells into defectors, engineering them to kill the tumors from whence they came, and have tested the approach in mice.