Molecular Imaging Pioneer, Sanjiv “Sam” Gambhir, Dies at 57
Molecular Imaging Pioneer, Sanjiv “Sam” Gambhir, Dies at 57
The Stanford Medical School professor’s research aided the development of positron emission tomography (PET) reporters to identify disease.
Molecular Imaging Pioneer, Sanjiv “Sam” Gambhir, Dies at 57
Molecular Imaging Pioneer, Sanjiv “Sam” Gambhir, Dies at 57

The Stanford Medical School professor’s research aided the development of positron emission tomography (PET) reporters to identify disease.

The Stanford Medical School professor’s research aided the development of positron emission tomography (PET) reporters to identify disease.

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glioblastoma

Zika as Cancer Buster?
Amy Schleunes | Apr 1, 2020
By infecting glioblastoma cells but not healthy brain tissue, some form of the virus could serve a therapeutic purpose.
CAR T Cell Adds Scorpion Venom to Tackle Tumor Heterogeneity
Amy Schleunes | Mar 24, 2020
A newly engineered CAR T cell that incorporates a peptide isolated from the venom of the deathstalker scorpion has broad brain tumor–binding capabilities that will be investigated in an upcoming clinical trial.
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A New Model with Fully Functioning Blood Vessels Mimics Brain Cancer
Roni Dengler, PhD | Sep 10, 2021
A newly developed platform may one day replace cell culture and animal models to personalize cancer treatment.
Air Pollution Tied to Brain Cancer: Study
Emily Makowski | Nov 13, 2019
Inhaling combustion-produced particles may lead to the development of brain tumors.
Immune-Activating Gene Therapy for Glioblastoma
Ruth Williams | Aug 14, 2019
The results of an early trial in 31 brain cancer patients finds immune activity boosted in the tumor, and possibly longer survival.
The Structure and Functions of the p53 Pathway: Information Acquisition, Redundancy, and Connectivity
The Scientist Creative Services Team | Jun 5, 2020
Arnold Levine will discuss his discovery of p53 and the evolution of the field since then, and Jon Chen will discuss the use of single-cell phosphoproteomics in identifying changes in key signaling networks, including p53.
brain tissue
Glioblastoma on a Chip
Jef Akst | Jul 15, 2019
Researchers use 3-D printing technology to construct a brain cancer model that accurately recapitulated in vivo biology and predicted patient drug responses.
brain tissue
Infographic: A 3-D Printed Brain Tumor
Jef Akst | Jul 15, 2019
How researchers create a glioblastoma on a chip that can predict patients’ response to treatments
cancer more common in men
Why Is Cancer More Common in Men Than in Women?
Jef Akst | Apr 1, 2019
The molecular processes that lead males to be more susceptible to the disease are only beginning to come to light.
CAR Ts solid tumor
The Next Frontier of CAR T-Cell Therapy: Solid Tumors
Kerry Grens | Apr 1, 2019
The technology has wowed the field by all but obliterating some patients’ blood cancers, but solid malignancies present new challenges.
Traitorous Tumor Cells Kill Their Own Kind
Ruth Williams | Jul 11, 2018
Researchers plan to turn cancer cells into defectors, engineering them to kill the tumors from whence they came, and have tested the approach in mice.
Poliovirus Therapy May Extend Lives of Advanced Brain-Cancer Patients
Ashley Yeager | Jun 26, 2018
More than one-fifth of individuals treated with the genetically modified virus survived at least three years.
PD-L1 in Extracellular Vesicles May Help Glioblastoma Evade Immunotherapies
Jim Daley | Mar 8, 2018
The discovery suggests that the immune checkpoint can operate at a further distance from tumor cells than previously believed.
Immune Cells Deliver Cancer Drugs to the Brain
Diana Kwon | Jun 19, 2017
Neutrophils loaded with the chemotherapy drug paclitaxel traverse the blood-brain barrier and kill residual cancer cells after tumor-resection surgery in mice.
Distinguishing Circulating Tumor from Normal Cell-Free DNA
Alison F. Takemura | Jul 19, 2016
Fragments of circulating DNA from tumors are around 20 to 30 base pairs shorter than those from healthy cells, researchers report.