The Next Frontier of CAR T-Cell Therapy: Solid Tumors
Kerry Grens | Apr 1, 2019
The technology has wowed the field by all but obliterating some patients’ blood cancers, but solid malignancies present new challenges.
Why Is Cancer More Common in Men Than in Women?
Why Is Cancer More Common in Men Than in Women?
The molecular processes that lead males to be more susceptible to the disease are only beginning to come to light.
The molecular processes that lead males to be more susceptible to the disease are only beginning to come to light.
Traitorous Tumor Cells Kill Their Own Kind
Ruth Williams | Jul 11, 2018
Researchers plan to turn cancer cells into defectors, engineering them to kill the tumors from whence they came, and have tested the approach in mice.
Poliovirus Therapy May Extend Lives of Advanced Brain-Cancer Patients
Ashley Yeager | Jun 26, 2018
More than one-fifth of individuals treated with the genetically modified virus survived at least three years.
PD-L1 in Extracellular Vesicles May Help Glioblastoma Evade Immunotherapies
Jim Daley | Mar 8, 2018
The discovery suggests that the immune checkpoint can operate at a further distance from tumor cells than previously believed.
Immune Cells Deliver Cancer Drugs to the Brain
Diana Kwon | Jun 19, 2017
Neutrophils loaded with the chemotherapy drug paclitaxel traverse the blood-brain barrier and kill residual cancer cells after tumor-resection surgery in mice.
Distinguishing Circulating Tumor from Normal Cell-Free DNA
Alison F. Takemura | Jul 19, 2016
Fragments of circulating DNA from tumors are around 20 to 30 base pairs shorter than those from healthy cells, researchers report.