p53 Unleashes Endogenous Retroviruses to Tackle Tumors: Study
p53 Unleashes Endogenous Retroviruses to Tackle Tumors: Study
New experiments suggest the famous tumor-suppressing protein uses viral elements lingering in the genome to get cancerous cells to announce their presence to the immune system.
p53 Unleashes Endogenous Retroviruses to Tackle Tumors: Study
p53 Unleashes Endogenous Retroviruses to Tackle Tumors: Study

New experiments suggest the famous tumor-suppressing protein uses viral elements lingering in the genome to get cancerous cells to announce their presence to the immune system.

New experiments suggest the famous tumor-suppressing protein uses viral elements lingering in the genome to get cancerous cells to announce their presence to the immune system.

cancer therapeutics
Boosting CAR T Cell Therapy for Solid Tumors
Boosting CAR T Cell Therapy for Solid Tumors
The Scientist Creative Services Team in Collaboration with IsoPlexis | Apr 5, 2021
Katie McKenna will discuss how oncolytic viral therapy enhances CAR-T cell killing of cancer cells.
Checking Checkpoints for Treating Cancer
Checking Checkpoints for Treating Cancer
The Scientist Creative Services Team | Mar 31, 2021
Researchers devise strategies to improve checkpoint inhibitor therapy and predict patient response.
José Baselga, Renowned Oncologist, Dies at 61
José Baselga, Renowned Oncologist, Dies at 61
Asher Jones | Mar 22, 2021
The cancer researcher and executive vice president of AstraZeneca’s oncology research and development is well known for his role in the development of pivotal breast cancer therapies.
Surveillance Gaps: How Cancer Arises
Surveillance Gaps: How Cancer Arises
The Scientist Creative Services Team | Mar 15, 2021
Surveillance Gaps: How Cancer Arises
Bispecific Antibodies Treat Cancer in Mouse Models
Bispecific Antibodies Treat Cancer in Mouse Models
Abby Olena | Mar 5, 2021
A trio of papers shows that specialized antibodies can direct T cells to destroy cells that display portions of mutant cancer-related proteins, as well as T cells that have become cancerous themselves.
Perfecting Dose Response Assays
Perfecting Dose Response Assays
The Scientist Creative Services Team | Feb 4, 2021
Jeffrey Weidner and Eric Niederkofler will discuss strategies for optimizing dose response assays.
Blocking Cancer Progression and Shrinking Tumors with Antibody-ligand Traps
Blocking Cancer Progression and Shrinking Tumors with Antibody-ligand Traps
The Scientist Creative Services Team | Dec 4, 2020
LuZhe Sun will discuss TGFβ signaling during cancer progression and how researchers can target this pathway.
The Structure and Functions of the p53 Pathway: Information Acquisition, Redundancy, and Connectivity
The Structure and Functions of the p53 Pathway: Information Acquisition, Redundancy, and Connectivity
The Scientist Creative Services Team | Jun 5, 2020
Arnold Levine will discuss his discovery of p53 and the evolution of the field since then, and Jon Chen will discuss the use of single-cell phosphoproteomics in identifying changes in key signaling networks, including p53.
Infographic: Exercise’s Anticancer Mechanisms
Infographic: Exercise’s Anticancer Mechanisms
Bente Klarlund Pedersen | Apr 1, 2020
A look at the molecular processes that may feed into the tumor-fighting effects of physical activity
CRISPR Quashes Cancer in Mice
CRISPR Quashes Cancer in Mice
Rachael Moeller Gorman | Apr 1, 2020
Gene editing can knock out genes crucial to cervical tumor cells’ survival, researchers report.
Regular Exercise Helps Patients Combat Cancer
Regular Exercise Helps Patients Combat Cancer
Bente Klarlund Pedersen | Apr 1, 2020
Studies point to a role for physical activity in fighting malignancies, improving treatment outcomes, and fostering overall health in patients.
Infographic: CRISPR’d Cancer
Infographic: CRISPR’d Cancer
Rachael Moeller Gorman | Apr 1, 2020
Researchers use a new way to deliver CRISPR/Cas9 to tumors in mice, wiping out the cancer.
Glioblastoma on a Chip
Glioblastoma on a Chip
Jef Akst | Jul 15, 2019
Researchers use 3-D printing technology to construct a brain cancer model that accurately recapitulated in vivo biology and predicted patient drug responses.
Infographic: A 3-D Printed Brain Tumor
Infographic: A 3-D Printed Brain Tumor
Jef Akst | Jul 15, 2019
How researchers create a glioblastoma on a chip that can predict patients’ response to treatments
Scientists Take Aim at Disease-Causing RNAs Using Small-Molecule Drugs
Scientists Take Aim at Disease-Causing RNAs Using Small-Molecule Drugs
Claire Asher | Apr 1, 2019
Renewed interest from the biotech industry sparks hope for drugging the nucleic acid to treat cancer and other conditions.
Traitorous Tumor Cells Kill Their Own Kind
Traitorous Tumor Cells Kill Their Own Kind
Ruth Williams | Jul 11, 2018
Researchers plan to turn cancer cells into defectors, engineering them to kill the tumors from whence they came, and have tested the approach in mice.
Poliovirus Therapy May Extend Lives of Advanced Brain-Cancer Patients
Poliovirus Therapy May Extend Lives of Advanced Brain-Cancer Patients
Ashley Yeager | Jun 26, 2018
More than one-fifth of individuals treated with the genetically modified virus survived at least three years.
A T-Cell Tweak Combats Advanced Breast Cancer
A T-Cell Tweak Combats Advanced Breast Cancer
Ashley Yeager | Jun 5, 2018
The immunotherapy eliminated a woman’s metastatic lesions and kept her disease-free for two years.
World’s Largest Cell and Gene Therapy Plant Opens
World’s Largest Cell and Gene Therapy Plant Opens
Catherine Offord | Apr 10, 2018
Lonza will employ more than 200 full-time staff to work at the Texas-based facility, the company says.