ISTOCK, DR_MICROBEResearchers have developed a compound that blocks the replication of rhinoviruses, the pathogens behind most cases of the common cold. The in vitro study, published yesterday (May 14) in Nature Chemistry, could provide the first step to developing a treatment for a condition that affects the average adult two to three times a year.
“The common cold is an inconvenience for most of us, but can cause serious complications in people with conditions like asthma and [chronic obstructive pulmonary disease],” study coauthor Ed Tate of Imperial College London says in a statement. “A drug like this could be extremely beneficial if given early in infection.”
Despite being so widespread, the common cold has consistently eluded effective medical treatment, both because of the vast number of viruses that cause it—more than 150 strains of rhinovirus infect humans—and because these pathogens are particularly fast-evolving.
Instead of trying to target the viruses themselves, a team led by researchers at Imperial focused its sights on a human enzyme that the viruses hijack to assemble their protein coats after invading cells. Blocking this enzyme ...
