Researchers Find DNA “Borgs” in Methane-Chomping Archaea

Massive extrachromosomal elements named after the hive-minded cyborg villains in Star Trek may be the first of their kind.

Written byAnnie Melchor
| 3 min read
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Update (October 26, 2022): The study referenced in this story has now been published in Nature.

Researchers have discovered what may be a novel form of giant, extrachromosomal DNA in mud-dwelling archaea, according to a preprint posted on bioRxiv last week (July 12).

They’re “not like anything that’s been seen before,” University of Texas microbiologist Brett Baker, who was not involved in the study, tells Nature.

Extrachromosomal elements (ECE) include structures such as viruses, plasmids, and megaplasmids, and contribute to features such as antibiotic resistance in bacteria. But according to the paper, the newly discovered structures, which the researchers call Borgs, weigh in at between 600,000 and more than 1 million base pairs—far too big to fit into any of these known ECE categories. According to University of California, Berkeley, geomicrobiologist Jill Banfield, who led the study, that’s about one-third the size ...

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    Stephanie "Annie" Melchor got her PhD from the University of Virginia in 2020, studying how the immune response to the parasite Toxoplasma gondii leads to muscle wasting and tissue scarring in mice. While she is still an ardent immunology fangirl, she left the bench to become a science writer and received her master’s degree in science communication from the University of California, Santa Cruz, in 2021. You can check out more of her work here.

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