Crystal structure of adeno-associated virus serotype 3B
| 1 min read
As the demand for viral vectors rises in new gene therapy approaches, scientists seek ways to optimize their production.

plasmids

Conceptual vector image of scientist engage in molecular biology research.

Helper Plasmids Lend a Hand to AAV Production

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A scientist in a laboratory looks surprised. She holds a tube in one hand. 

A Miscalculated Step

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Resolving Large DNA Fragments with Ease

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Conceptual vector illustration depicting CRISPR gene editing by scientists for medical applications.

Optimizing Gene Editing with PARP1 CRISPR Plasmids 

Frozen laboratory test tubes in box container in a research lab.

Save the Sample

Doug Hanahan worked at Cold Spring Harbor Laboratory in 1982. 

Cellular Competence: Making Recombinant DNA Accessible

Discover How to Verify Plasmid Quality with the Agilent Fragment Analyzer System

Analyzing Plasmids with Automated Electrophoresis

Multiplexed and Trackable CRISPR-Based Genome Engineering

A Platform for Automated CRISPR-Based Microbial Genome Engineering

Automating Bacterial Plasmid Purification

Automating DNA Extraction for High-Throughput Bacterial Plasmid Purification

Technique Talk: Cell Transfection Techniques

Technique Talk: Cell Transfection Techniques

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Researchers Find DNA “Borgs” in Methane-Chomping Archaea

Optimizing Adeno-Associated Virus (AAV) Manufacturing

Taming the Transposon Hordes

Stanley Falkow, Father of Molecular Microbial Pathogenesis, Dies

Gene Editing Without Foreign DNA

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Sharing Made Easy

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Image of a DNA strand with a magnifying glass hovering over one section (left). A sweating man lifts his arm and emits body odor with a callout depicting that he has yellow colored earwax (right).

How Are Earwax and Body Odor Linked?

Image of colorful microplastics against a black background.

Microplastics Build Up in Human Organs, Especially the Brain

Close-up shot of hands as they type on a laptop.

Postdocs Who Publish Hit Papers Are More Likely to Stay and Succeed in Academia

A picture of the main building of the National Institutes of Health (NIH).

Freeze on NIH Grant Reviews Leaves Scientists Confused and Frustrated

Multimedia

Explore a Concise Guide to Optimizing Viral Transduction

A Visual Guide to Lentiviral Gene Delivery

Takara Bio
An illustration of differently shaped viruses.

Detecting Novel Viruses Using a Comprehensive Enrichment Panel

Twist Bio 
3D illustration of a gold lipid nanoparticle with pink nucleic acid inside of it. Purple and teal spikes stick out from the lipid bilayer representing polyethylene glycol.
February 2025, Issue 1

A Nanoparticle Delivery System for Gene Therapy

A reimagined lipid vehicle for nucleic acids could overcome the limitations of current vectors.

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Considerations for Cell-Based Assays in Immuno-Oncology Research

Considerations for Cell-Based Assays in Immuno-Oncology Research

Lonza
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From Water Bears to Grizzly Bears: Unusual Animal Models

Taconic Biosciences
Sex Differences in Neurological Research

Sex Differences in Neurological Research

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New Frontiers in Vaccine Development

New Frontiers in Vaccine Development

Sino

Products

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Tecan introduces Veya: bringing digital, scalable automation to labs worldwide

Explore a Concise Guide to Optimizing Viral Transduction

A Visual Guide to Lentiviral Gene Delivery

Takara Bio
Inventia Life Science

Inventia Life Science Launches RASTRUM™ Allegro to Revolutionize High-Throughput 3D Cell Culture for Drug Discovery and Disease Research

An illustration of differently shaped viruses.

Detecting Novel Viruses Using a Comprehensive Enrichment Panel

Twist Bio