Lung cancer cellsWIKIMEDIA COMMONS
By activating an enzyme involved in the breakdown of glucose, researchers were able to slow the growth of lung cancer cells and increase the harm inflicted by reactive oxygen species (ROS)—byproducts of normal metabolism that can cause damage to the cell in high concentrations. The findings, published Thursday (November 3) in Science Express, could one day be used to make cancer cells more susceptible to cancer treatments and minimize tumor growth.
“It’s a beautiful paper, very elegant,” said cancer biologist Karen Vousden of the Beatson Institute for Cancer Research in Glasgow, who was not involved in the study. The study shows how tumors normally cope so well with increased oxidative stress and provides an avenue to turn that mechanism against the cancer, she said.
Scientists ...
