Skip to main content

Sniffing Out TB

An African rat helps detect tuberculosis in Tanzania, prompting the Mozambique government to pursue a similar project.

Written byJef Akst
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00

African pouched rat, WikimediaThe Belgian NGO Apopo is on the hunt for the life-threatening bacterium that causes tuberculosis (TB), and it is finding it using an unlikely helper—the African giant pouched rat, so named for its paunchy cheek pouches. After a bit of training, the rats can identify a distinctive TB smell—caused by organic compounds the bacterium produces in infected samples—in a fraction of a second, tackling as many as 1,680 samples per day, The Hindu reported. To put that in perspective, a trained lab tech can screen about 40 samples per day, a number that takes a pouched rat just 7 minutes.

The organization has been using the rats as a secondary screening method in hospitals, screening more than 97,000 samples and upping detection rates by as much as 23 percent. The success of the project caught the attention of the Mozambique government, which has asked Apopo to set up a similar screening effort in the country. “We are in the process of setting up a laboratory and training handlers,” Apopo representative Tess Tewelde told The Hindu. “The program will kick in by December.”

The projects add to the growing number of animals being used to detect disease. Dogs, for example, are being trained to identify and even differentiate among a variety of human cancers. Bees have also showed promising abilities in recognizing TB volatiles.

And the ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member?
Add The Scientist as a preferred source on Google

Add The Scientist as a preferred Google source to see more of our trusted coverage.

Meet the Author

  • Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.

    View Full Profile

Related Topics

Related articles background image
The Scientist Digest cover September 2026
September 2026

Multiplex Microscopy Becomes Easier with Encoded Antibodies

A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies.

View this Issue
Essential Genes Are Dominantly Activated by Single Transcription Factors

Essential Genes Are Dominantly Activated by Single Transcription Factors

EpiCypher Logo
Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Alamar Biosciences logo
Engineering CAR-Neutrophils In Vivo to Target Glioblastoma

Engineering CAR-Neutrophils In Vivo to Target Glioblastoma

Miltenyi
Best Practices for qPCR Assay Design and Optimization

Best Practices for qPCR Assay Design and Optimization

Bio-Rad

Products

Closeup image of a multi channel pipette dispensing pink liquid into a 96-well plate.

The ASSIST PLUS pipetting robot for affordable workflow automation

Integra Logo
Single cells in suspension

Rapidly isolate primary cells and make uniform single-cell suspensions with Corning® Cell Strainers

Corning logo
Abstract image representing cell membranes linked together.

CellBrite® Steady Membrane Stain: Cell surface staining built for real-time imaging

Biotium
sino biological logo

Monod Bio Licenses AI-designed Protein Technologies to SignalChem Biotech for Custom Discovery Assays