Sophia Lunt Traces the Effect of Metabolism on Cancer Metastasis

The Michigan State University researcher’s lab experiences shaped her interest in the role of glucose in cancer’s spread.

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sophia lunt scientist to watch soap mice’s tumor metabolites

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Above: © doug coombe Photography

Sophia Lunt’s career in cancer research started with soap.“Soap is both polar and nonpolar, so it binds to nonpolar grease and also to polar water when you go to wash it away,” the Michigan State University chemist says, recalling a high school science lesson. “I thought that was really cool and wanted to learn more about molecules.”

Lunt attended Lebanon Valley College in Annville, Pennsylvania, and majored in chemistry. She graduated in 2005, and not long after started her PhD at Princeton University, eventually joining the lab of chemist Joshua Rabinowitz. There, she published research (under her maiden name Kwon) on how anti-metabolite drugs affect metabolism to stop bacterial growth.1

After earning her PhD in 2010, she wanted to connect chemistry to human disease, so she joined Matthew Vander Heiden’s cancer metabolism lab as a postdoc at MIT. Lunt was fascinated by the Warburg effect—the ...

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  • Ashley Yeager

    Ashley started at The Scientist in 2018. Before joining the staff, she worked as a freelance editor and writer, a writer at the Simons Foundation, and a web producer at Science News, among other positions. She holds a bachelor’s degree in journalism from the University of Tennessee, Knoxville, and a master’s degree in science writing from MIT. Ashley edits the Scientist to Watch and Profile sections of the magazine and writes news, features, and other stories for both online and print.

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