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Two cells fluorescently stained for normal (red) and damaged (green) lysosomes.
Cancer Cells Spread When They Stop Recycling Waste
An immune-inhibiting protein that regulates autophagy halts breast cancers from venturing across tissue borders.
Cancer Cells Spread When They Stop Recycling Waste
Cancer Cells Spread When They Stop Recycling Waste

An immune-inhibiting protein that regulates autophagy halts breast cancers from venturing across tissue borders.

An immune-inhibiting protein that regulates autophagy halts breast cancers from venturing across tissue borders.

breast cancer

Larger green cell with two cyan spots and many smaller magenta circles in and around the cell. 
Synthetic Systems for Studying Natural Cells
Danielle Gerhard, PhD | Jun 3, 2024 | 2 min read
Oskar Staufer engineers synthetic systems to explore cancer biology.
3D rendered DNA strand and cancer cell 
Translating ctDNA Detection into Breast Cancer Research Breakthroughs
The Scientist Staff | May 1, 2024 | 2 min read
Noninvasive methods to monitor traces of cancer left over after treatment may lead to better early interventions.
Defining the Triple Negative Breast Cancer Morpholome
Defining the Triple Negative Breast Cancer Morpholome
The Scientist Staff | 1 min read
Learn how researchers take a phenotype-first approach to uncover hidden metastatic drivers at tissue and cellular levels.
A microscopy image stained for different cell populations in breast tumors.
Cancer Cells Give Orders
Holly Barker, PhD | Apr 23, 2024 | 4 min read
Cancer-supporting cells control their neighbors’ behavior using an often-overlooked protein delivery system. 
Artistic rendering of a cancer cell in red with round, blue accents
Targeting Breast Cancer Metastasis
Tanvir Khan, PhD | Oct 16, 2023 | 3 min read
Researchers inhibited molecules that regulate both tumor and immune cell migration and their crosstalk signaling to impede metastasis.
A colorful bouquet of fruits and vegetables in a mesh canvas bag.
Beyond Individual Nutrients: Complex Diet and Cancer Connections
Deanna MacNeil, PhD | 4 min read
Scientists develop cancer nutrition guidelines based on research examining how dietary patterns affect cancer risk and prevention.
Carolyn Bertozzi working in the laboratory with postdoctoral scholar Ula Gerling-Driessen
Trimming Undruggable Cancer Targets
Deanna MacNeil, PhD | Sep 13, 2023 | 4 min read
Researchers took aim at mucins, glycoproteins that protect cancer cells from drugs and the immune response, and engineered a revolutionary targeted tool for oncology and beyond.
Histological stain of in blue, red, and green of tumor
Self-Charging Battery Battles Tumors in Mice
Natalia Mesa, PhD | Apr 4, 2023 | 3 min read
A battery that charges itself in salty fluids starves tumors of oxygen, helping improve some drugs treat cancer, a study finds.
Human DNA stock photo
Setting Better Traps for PARP Inhibitors
The Scientist and BPS Bioscience | 4 min read
An innovative assay permits researchers to screen for small molecule PARP inhibitors that trap the enzyme on DNA and selectively execute cancer cells.
Fluorescent image of breast tissue
Hormone Therapy Triggers Male Gene Patterns in Transgender Men’s Cells
Holly Barker, PhD | Mar 15, 2023 | 3 min read
A study deepens the scientific understanding of how androgens influence breast tissue, which may offer clues to treating breast cancer. 
A colored microscopy image of a dividing breast cancer cell
Transfer RNAs Have a Surprising Role in Breast Cancer Growth
Natalia Mesa, PhD | Jan 5, 2023 | 4 min read
A particular leucine-ferrying tRNA is more abundant in cancerous cells than healthy ones, and lowering its levels inhibits cancer growth, a study finds.
Modeling the Complexity of Human Tumors in 3-D Cell Cultures
Technique Talk: Modeling the Complexity of Human Tumors in 3-D Cell Cultures
The Scientist | 1 min read
In this workshop, learn how to make precision medicine a reality by modeling human cancers in 3-D organoid cultures for drug screening.
A purple-stained section of an invasive breast cancer growth. The dark purple non-fatty tissue takes up the majority of the frame, and pale purple circular tumors grow in ducts in the bottom left.
Harboring Hard and Soft Cells Lets Tumors Grow and Metastasize Simultaneously
Katherine Irving | Oct 17, 2022 | 4 min read
Islands of rigid cells within a matrix of soft ones allow tumors to be both solid and fluid, granting them toughness without losing the ability to break apart.
jigsaw puzzle with magnifying glass over the word "metastasis" 
Breast Cancer Cells Retrain T Cells to Invade Specific Tissues
Nele Haelterman, PhD | Sep 26, 2022 | 3 min read
Scientists discover tumor-associated T cells that drive breast cancer metastasis to lymph nodes.
Understanding Cancer Evolution Through the Lens of Single Cell Genomics
Understanding Cancer Evolution Through the Lens of Single Cell Genomics
The Scientist | 1 min read
Nicholas Navin and Lars Velten discuss sampling, sequencing, and tracing single cells to study how cancer cells adapt to various environments.
Artist’s rendition of metastatic cancer cells with yellow nuclei and green cell bodies extending into blue tendrils.
While the Body Rests, Breast Cancer Spreads More Aggressively
Alejandra Manjarrez, PhD | Jun 23, 2022 | 4 min read
More cancer cells are shed from primary tumors when individuals are asleep than when they’re awake, according to observations in mouse models and a small cohort of breast cancer patients.
illustration of a blood vessel
Bacteria in Tumors Promote Metastasis in Mice
Sophie Fessl, PhD | Apr 7, 2022 | 3 min read
Microbes living inside cancer cells may help them spread to distant sites by enhancing the cells’ resistance to mechanical stress, a study shows.
Cancer Vaccines: Raising a T Cell Army
Niki Spahich, PhD | 1 min read
Vaccines against various forms of cancer prime the immune system to attack.
A photo of a triple-negative breast cancer cell
A Fasting-Mimicking Diet Thwarts Breast Cancer in Mice
Devin A. Reese, PhD | Mar 1, 2022 | 2 min read
Coupling a diet low in calories, sugar, and protein with existing cancer drugs treats triple-negative breast cancer in mice, and low blood glucose is associated with better cancer outcomes in human patients.
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