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breast cancer

Artistic rendering of a cancer cell in red with round, blue accents

Tanvir Khan, PhD | Oct 16, 2023 | 3 min read

Researchers inhibited molecules that regulate both tumor and immune cell migration and their crosstalk signaling to impede metastasis.

Carolyn Bertozzi working in the laboratory with postdoctoral scholar Ula Gerling-Driessen

Trimming Undruggable Cancer Targets

Deanna MacNeil, PhD | Sep 13, 2023 | 4 min read

Researchers took aim at mucins, glycoproteins that protect cancer cells from drugs and the immune response, and engineered a revolutionary targeted tool for oncology and beyond.

A colorful bouquet of fruits and vegetables in a mesh canvas bag.

Beyond Individual Nutrients: Complex Diet and Cancer Connections

Deanna MacNeil, PhD | 4 min read

Scientists develop cancer nutrition guidelines based on research examining how dietary patterns affect cancer risk and prevention.

Hormone Therapy Triggers Male Gene Patterns in Transgender Men’s Cells

Holly Barker, PhD | Mar 15, 2023 | 3 min read

A study deepens the scientific understanding of how androgens influence breast tissue, which may offer clues to treating breast cancer.

A colored microscopy image of a dividing breast cancer cell

Transfer RNAs Have a Surprising Role in Breast Cancer Growth

Natalia Mesa, PhD | Jan 5, 2023 | 4 min read

A particular leucine-ferrying tRNA is more abundant in cancerous cells than healthy ones, and lowering its levels inhibits cancer growth, a study finds.

Setting Better Traps for PARP Inhibitors

The Scientist’s Creative Services Team and BPS Bioscience | 4 min read

An innovative assay permits researchers to screen for small molecule PARP inhibitors that trap the enzyme on DNA and selectively execute cancer cells.

A purple-stained section of an invasive breast cancer growth. The dark purple non-fatty tissue takes up the majority of the frame, and pale purple circular tumors grow in ducts in the bottom left.

Harboring Hard and Soft Cells Lets Tumors Grow and Metastasize Simultaneously

Katherine Irving | Oct 17, 2022 | 4 min read

Islands of rigid cells within a matrix of soft ones allow tumors to be both solid and fluid, granting them toughness without losing the ability to break apart.

jigsaw puzzle with magnifying glass over the word "metastasis"

Breast Cancer Cells Retrain T Cells to Invade Specific Tissues

Nele Haelterman, PhD | Sep 26, 2022 | 3 min read

Scientists discover tumor-associated T cells that drive breast cancer metastasis to lymph nodes.

Technique Talk: Modeling the Complexity of Human Tumors in 3-D Cell Cultures

The Scientist’s Creative Services Team | 1 min read

In this workshop, learn how to make precision medicine a reality by modeling human cancers in 3-D organoid cultures for drug screening.

Artist’s rendition of metastatic cancer cells with yellow nuclei and green cell bodies extending into blue tendrils.

While the Body Rests, Breast Cancer Spreads More Aggressively

Alejandra Manjarrez, PhD | Jun 23, 2022 | 4 min read

More cancer cells are shed from primary tumors when individuals are asleep than when they’re awake, according to observations in mouse models and a small cohort of breast cancer patients.

Bacteria in Tumors Promote Metastasis in Mice

Sophie Fessl, PhD | Apr 7, 2022 | 3 min read

Microbes living inside cancer cells may help them spread to distant sites by enhancing the cells’ resistance to mechanical stress, a study shows.

Understanding Cancer Evolution Through the Lens of Single Cell Genomics

The Scientist’s Creative Services Team | 1 min read

Nicholas Navin and Lars Velten discuss sampling, sequencing, and tracing single cells to study how cancer cells adapt to various environments.

A photo of a triple-negative breast cancer cell

A Fasting-Mimicking Diet Thwarts Breast Cancer in Mice

Devin A. Reese, PhD | Mar 1, 2022 | 2 min read

Coupling a diet low in calories, sugar, and protein with existing cancer drugs treats triple-negative breast cancer in mice, and low blood glucose is associated with better cancer outcomes in human patients.

health care provider standing in front of gynecology stirrups holding swabs for Pap smear

DNA Methylation Could Predict Ovarian, Breast Cancers

Anna Napolitano, PhD | Feb 11, 2022 | 5 min read

A pair of new studies finds that analyzing material from a Pap smear can reveal tumor risk in distant parts of the body, potentially allowing early interventions.