Stress-Response Compound Widespread in Animals Is Found in Plants

TMAO appears to both stabilize other plant proteins and influence the expression of stress-response genes, researchers report.

Written byShawna Williams
| 4 min read
two tomato plants in pots viewed from the top, one scraggly with yellow leaves and one healthier-looking

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ABOVE: Tomato plants watered with a high-salt solution. The water of the plant on the right was supplemented with TMAO, while that of the plant on the left was not.
RAFAEL CATALÁ

A molecule made famous by its association with human heart disease and marine animals’ ability to survive high-pressure conditions turns out to be made by plants too, researchers report this week (May 19) in Science Advances. As it does in animals, trimethylamine N-oxide (TMAO) helps plants cope with stressful conditions, according to the study. The authors have already licensed the discovery to a company that is working to commercialize TMAO as a way to boost yields in agriculture.

“Nobody has published before that plants have TMAO in the tissues,” says study coauthor Rafael Catalá of the Centro de Investigaciones Biológicas (CIB) Margarita Salas in Madrid.

The new study grew out of earlier work in which Catalá and his colleagues ...

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  • Shawna was an editor at The Scientist from 2017 through 2022. She holds a bachelor’s degree in biochemistry from Colorado College and a graduate certificate in science communication from the University of California, Santa Cruz. Previously, she worked as a freelance editor and writer, and in the communications offices of several academic research institutions. As news director, Shawna assigned and edited news, opinion, and in-depth feature articles for the website on all aspects of the life sciences. She is based in central Washington State, and is a member of the Northwest Science Writers Association and the National Association of Science Writers.

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