Studies Identify Risk Factors for Long COVID

Two recent papers provide insight into possible risk factors for developing the chronic condition, including autoantibodies and diabetes.

Written byNatalia Mesa, PhD
| 4 min read
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For long COVID sufferers, feelings of fatigue, breathing difficulties, and other debilitating symptoms persist for weeks or months after infection with SARS-CoV-2. According to one estimate, up to 60 percent of people who’ve had COVID-19 still have symptoms six months later, and the condition can arise even after mild cases of the respiratory disease. The reason why remains largely a mystery.

Two new studies are finally providing some answers. The first, published in Cell on Monday (January 24), followed 200 patients over two to three months following their COVID-19 diagnoses. The researchers determined four biological factors that they say are associated with whether a person will develop long COVID. These factors, the researchers suggest, could point to ways to prevent or treat long COVID—also known as post-acute sequelae of COVID-19 (PASC)—if identified early in an infection.

The first factor is the level of RNA in the blood at diagnosis, which ...

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    As she was completing her graduate thesis on the neuroscience of vision, Natalia found that she loved to talk to other people about how science impacts them. This passion led Natalia to take up writing and science communication, and she has contributed to outlets including Scientific American and the Broad Institute. Natalia completed her PhD in neuroscience at the University of Washington and graduated from Cornell University with a bachelor’s degree in biological sciences. She was previously an intern at The Scientist, and currently freelances from her home in Seattle. 

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