The image depicts a lung cancer tri-culture model made with RASTRUM Allegro. Primary normal human lung fibroblasts (NHLFs) were printed with primary human umbilical vein endothelial cells (HUVECs) and A549 lung adenocarcinoma cells using RASTRUM’s Imaging Model architecture. Cells were cultured for 7 days and stained using a PhenoVue Cell Painting Kit (Revvity). Cell nuclei (cyan) were labeled with Hoescht, filamentous actin (yellow) with phalloidin, and membrane glycoproteins (magenta) with concanavalin A.
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Cameron Ferris from Inventia Life Science discusses how 3D cell culture provides predictive human-relevant insights that transform disease modeling and therapeutic screening.

3D cell culture

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The Era of Organoids: Disease Modeling, Developmental Research, and Drug Response Prediction 

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Scientists Get to the Heart of Blood Formation

Learn How 3D Cell Cultures Advance Tissue Regeneration

Organoids as a Tool for Tissue Regeneration Research 

Studying Organ Development and Disease Using Organoids

Studying Organ Development and Disease Using Organoids

The Future of Disease Modeling for Precision Medicine

The Future of Disease Modeling for Precision Medicine

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Expanding Cancer Cell Therapy with Stem Cell-Derived NK Cells

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Organoids in Space: The Next Frontier

3D rendered spheroids floating on a blue background.

Developing Homogenous 3D Neural Cultures for High Throughput Screening

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From the Expert: Júlia Crispim da Fontoura on 3D Cell Cultures

Optimizing Organoid Culture for Development and Disease Modeling

Optimizing Organoid Culture for Development and Disease Modeling

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Understanding the 3D Cell Culture Revolution

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Spheroids Assemble: Scale up Stem Cell Suspension Cultures

Discover the foundations and future of organoid research technologies.

Levitating Organoid Cultures to Reach                                   Higher Research Heights

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Organoids: The New Frontier

Illuminating Organs with Organoids

Illuminating Organs with Organoids

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Food for Thought: A Recipe for Regenerating Nerves

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Optimizing Organoid Models for Basic Research and Translational Applications

Fluorescence microscopy photograph of human skin depicting stained fibroblasts, key cells involved in wound healing.

Mimicking Tissue Mechanics for Better Wound Healing Models

A normal human liver organoid (left) stained with blue and red next to a fatty liver organoid (right) with lipid droplets stained yellow.

Working Together to Battle Fatty Liver Disorders

Learn About the Clinical Potential of 3D Organoids

Organoids: How Close Are We to The Clinic?

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Penguins Are Among the World’s Slowest-Evolving Birds: Study

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Universe 25 Experiment

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An AI-Powered Scientist Proposes a Treatment for Blindness

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Maternal Iron Deficiency Can Trigger Sex Reversal in Mouse Embryos

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Taking Control of Cellular Contamination with PCR Testing

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Rare Disease Research Gets a Boost from Automated NGS Solutions

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Image of small blue creatures called Nergals. Some have hearts above their heads, which signify friendship. There is one Nergal who is sneezing and losing health, which is denoted by minus one signs floating around it.
June 2025, Issue 1

Nergal Networks: Where Friendship Meets Infection

A citizen science game explores how social choices and networks can influence how an illness moves through a population.

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Unraveling Complex Biology with Advanced Multiomics Technology

Unraveling Complex Biology with Five-Dimensional Multiomics

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Resurrecting Plant Defense Mechanisms to Avoid Crop Pathogens

Resurrecting Plant Defense Mechanisms to Avoid Crop Pathogens

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Seeing and Sorting with Confidence

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Streamlining Microbial Quality Control Testing

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Agilent Unveils the Next Generation in LC-Mass Detection: The InfinityLab Pro iQ Series

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Pioneering Cancer Plasticity Atlas will help Predict Response to Cancer Therapies

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How Alderley Analytical are Delivering eXtreme Robustness in Bioanalysis