3D illustration of RNA polymerase (blue, middle) transcribing a segment of DNA (purple) into an RNA chain (red, extending to top).

| 10+ min read

The lac Operon: A Lesson in Simple Gene Regulation

The discovery of an inducible switch in Escherichia coli that controlled lactose metabolism offered the first clues into gene expression.

Short strands of RNA floating on a blue background

| 5 min read

Gene Silencing with RNA Interference

Illustration of a small microRNA in blue with additional microRNAs in the background.

| 5 min read

From Worm Anomaly to Nobel Prize: microRNAs Show Macro Impact

gene regulation

Black and gold sketch of Victor Ambros and Gary Ruvkun, the 2024 Nobel Prize laureates.

Nobel Prize for microRNA

Danielle Gerhard, PhDandSneha Khedkar | | 4 min read

iStock

All About Alternative Splicing

Amielle Moreno, PhD | | 7 min read

A microscopy image of a mouse embryo expressing the red fluorescent protein mCherry in the central nervous system.

Dynamic Enhancers Orchestrate Development

Mariella Bodemeier Loayza Careaga, PhD | | 2 min read

Twist

Synthetic Screens, Genes, and De Novo Proteins - A Special Podcast Series

Twist BioscienceandThe Scientist | | 2 min read

Conceptual 3D illustration of DNA with multicolored base pairs on a black background.

Understanding Cell Type Specific 3D Genome Structure and DNA Methylation

Velsera | | 1 min read

Individual bacterial transcriptomes each plotted as a single point create a ring-shaped structure.

Rapidly Dividing Bacteria Coordinate Gene Expression and Replication

Kamal Nahas, PhD | | 4 min read

Advancing Drug Discovery by Employing Synthetic Biology Tools

Advancing Drug Discovery by Employing Synthetic Biology Tools

Available on Demand

The Scientist's Journal Club: Transcriptomics

Available on Demand

Illustration of HIV virus

Viral Protein Behind Chronic Inflammation in People with HIV: Study

Natalia Mesa, PhD | | 3 min read

zebrafish in an aquarium

Epigenetics May Remember Ancestors’ Mutations

Holly Barker, PhD | | 4 min read

Blue 3D illustration of X-shaped chromosomes

X Chromosome Silenced in Some Cancers in Males

Natalia Mesa, PhD | | 3 min read

Ribonucleic acid strands consisting of nucleotides important for protein bio-synthesis

Katharina Höfer Probes the Machinery of Bacterial Gene Expression

Hannah Thomasy, PhD | | 4 min read

The Inside Scoop on Successful ATAC-seq Experiments

Technique Talk: The Inside Scoop on Successful ATAC-seq Experiments

Available on Demand

Integrating Single-Cell Transcriptomics and Proteomics: A New Era of Biological Research

Bridging the Gap: Integrating Single-Cell Transcriptomics and Proteomics

Available on Demand

An artist's rendition of an RNA molecule in light blue on a dark blue background

Same RNA Acts in Neurodegeneration and Cancer

Abby Olena, PhD | | 3 min read

Abstract illustration of DNA

Signaling Dynamics Fine-Tune Gene Expression

Ruth Williams | | 3 min read

A microscopy image of several endometrial stromal fibroblasts

Gene Offers Clue to How Human Labor Starts

Christie Wilcox, PhD | | 4 min read

illustration of multiple clocks arranged in the shape of a brain

How Early-Morning Light Exposure Makes Mice Less Depressed

Bianca Nogrady | | 4 min read

Cancer May Be Driven by DNA Outside of Chromosomes

Paul Mischel | | 10+ min read

Infographic: The Role of Extrachromosomal DNA in Cancer

Paul Mischel | | 2 min read

Page 1 of 3 - 47 Total Items

Trending

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

A red male cardinal and a brownish female sit on a branch in front of a green background.

Sex Determination: It’s in the Genes—Sometimes

Animals across the tree of life have developed a mind-boggling variety of ways to become male or female.

A group of large animals, some of which are being studied for cancer resistance genes and proteins, are pictured, including a bison, an elephant, a giraffe, a manatee, a zebra, and a whale.

Peto’s Paradox: How Gigantic Species Evolved to Beat Cancer

Scientists dive into the genomes of whales, elephants, and other animal giants looking for new weapons in the fight against cancer.

A cross-section of a mouse brain with staining for NOVA1 and cell nuclei.

Strange Squeaks: A Uniquely Human Gene Alters Mouse “Songs”

A human-specific NOVA1 variant changed mouse vocalizations, potentially providing insights into the evolution of language.

Multimedia

Discover the history, mechanics, and potential of PCR.

Become a PCR Pro

Learn how mastering the ins and outs of PCR can accelerate workflows and improve data.

Understanding Disease Through Biomarkers

Understanding Disease Through Biomarkers

Learn how scientists identify and characterize biomarkers for cancer, neurodegenerative diseases, and autoimmune disorders.

A greyscale image of cells dividing.

March 2025, Issue 1

How Do Embryos Know How Fast to Develop

In mammals, intracellular clocks begin to tick within days of fertilization.

View this Issue

Research Resources

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Discover the history, mechanics, and potential of PCR.

Become a PCR Pro

Learn how mastering the ins and outs of PCR can accelerate workflows and improve data.

Explore polypharmacology’s beneficial role in target-based drug discovery

Embracing Polypharmacology for Multipurpose Drug Targeting

Polypharmacology allows scientists to explore novel therapeutic purposes for existing drugs and opens new doors to treat multifactorial diseases.

3D rendered cross section of influenza viruses, showing surface proteins on the outside and single stranded RNA inside the virus

Genetic Insights Break Infectious Pathogen Barriers

Molecular detection technologies help scientists rapidly and reliably find and address ever-evolving pathogens with optimal accuracy and sensitivity.

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Navigating Cold Storage Solutions

Discover the key features to consider when selecting a new refrigerator or freezer

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Gilead’s Capsid Revolution Meets Our Capsid Solutions: Sino Biological – Engineering the Tools to Outsmart HIV

On February 18, 2025, Gilead Sciences announced a significant milestone: the U.S. FDA accepted their New Drug Applications (NDAs) for lenacapavir (LEN), a groundbreaking twice-yearly injectable HIV-1 capsid inhibitor for pre-exposure prophylaxis (PrEP).

Stirling Ultracold

Meet the Upright ULT Built for Faster Recovery - Stirling VAULT100™

Slow temperature recovery can threaten the integrity of your work. That’s Stirling Ultracold designed the VAULT100™ to operate at setpoints down to -100°C, so your samples may never be exposed to temperatures above -70°C during a typical door opening.

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ChemiDoc Go Imaging System

The next generation imager from the ChemiDoc Imaging System line. Effortlessly capture gel and western blot images from your benchtop without compromising on sensitivity and precision.

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Evotec Announces Key Progress in Neuroscience Collaboration with Bristol Myers Squibb

• Ongoing strategic partnership advances joint pipeline in neurodegeneration research
• Evotec receives a $20 million payment to further progress research

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