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Uncovering Functions of Circular RNAs
Catherine Offord | Jul 17, 2017
Recent research has revealed many surprises about circular RNAs, from findings that they are translated in vivo to links between their expression and disease.
Wanted: Transcriptional Regulators
Ruth Williams | Aug 1, 2016
Researchers have designed a screen to find unique molecules, called riboswitches, that determine whether transcription will proceed.
Ruth Williams | Jul 31, 2016
A newly developed method detects regulators of bacterial transcription called riboswitches.
RNA Methylation Dynamics
and Gidi Rechavi, Dan Dominissini, Chuan He | Jan 1, 2016
Additions to the bases of RNA molecules can be written, read, and erased.
Metazoans in the DNAi Club
Amanda B. Keener | Jul 1, 2015
A chance discovery results in the first report of DNA-based gene silencing in an animal.
Jenny Rood | Jun 1, 2015
A chromatin remodeler in embryonic stem cells clears the DNA for mRNA transcription while stifling the expression of noncoding transcripts.
Exploring the Impacts of Genetic Variation on Tissue-Specific Expression
Jenny Rood | May 7, 2015
Preliminary results from the Genotype-Tissue Expression project reveal that gene expression varies more across tissues than across individuals.
Kate Yandell | Mar 1, 2015
Not only do telomeres protect the ends of chromosomes, they also modulate gene expression over cells’ lifetimes.
Similarities and Differences
Molly Sharlach | Nov 21, 2014
Results from the Mouse ENCODE project point to key divergences in gene regulation architecture compared to humans.
Eric Olson | Nov 1, 2014
The recent discovery of super-enhancers may offer new drug targets for a range of diseases.