Image of expression patterns of predicted target de novo genes. These are depicted as bars of varying shades from white, red, and blue.

| 4 min read

How Are De Novo Genes Regulated?

Computational research in fruit flies revealed how spontaneously arising genes are tightly controlled, offering insights into evolution.

3D illustration of RNA polymerase (blue, middle) transcribing a segment of DNA (purple) into an RNA chain (red, extending to top).

| 10+ min read

The lac Operon: A Lesson in Simple Gene Regulation

Short strands of RNA floating on a blue background

| 5 min read

What Is RNAi? Gene Silencing Explained for Researchers and Innovators

gene regulation

Illustration of a small microRNA in blue with additional microRNAs in the background.

From Worm Anomaly to Nobel Prize: microRNAs Show Macro Impact

Danielle Gerhard, PhD | | 5 min read

Black and gold sketch of Victor Ambros and Gary Ruvkun, the 2024 Nobel Prize laureates.

Nobel Prize for microRNA

Danielle Gerhard, PhDandSneha Khedkar | | 4 min read

iStock

All About Alternative Splicing

Amielle Moreno, PhD | | 7 min read

A microscopy image of a mouse embryo expressing the red fluorescent protein mCherry in the central nervous system.

Dynamic Enhancers Orchestrate Development

Mariella Bodemeier Loayza Careaga, PhD | | 2 min read

Twist

Synthetic Screens, Genes, and De Novo Proteins - A Special Podcast Series

Twist BioscienceandThe Scientist | | 2 min read

Conceptual 3D illustration of DNA with multicolored base pairs on a black background.

Understanding Cell Type Specific 3D Genome Structure and DNA Methylation

Velsera | | 1 min read

Individual bacterial transcriptomes each plotted as a single point create a ring-shaped structure.

Rapidly Dividing Bacteria Coordinate Gene Expression and Replication

Kamal Nahas, PhD | | 4 min read

Advancing Drug Discovery by Employing Synthetic Biology Tools

Advancing Drug Discovery by Employing Synthetic Biology Tools

Available on Demand

The Scientist's Journal Club: Transcriptomics

Available on Demand

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Trending

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

Illustration of a hole in the shape of a dollar sign on a blue background. One character is falling into the hole at the bottom of the “S” while another individual is holding another up at the top of the “S”. The image represents the absence of funding for researchers in biotech with the cancellation of the SBIR/STTR program.

The Federal Government’s Research Innovation Lifeline Has Gone Dark

Congressional inaction has led to the expiration of the federal government’s SBIR/STTR program, cutting off a biotechnology lifeline.

The green zombie virus under the microscope, on a mottled yellow background.

What Are Giant Viruses, and Are They Dangerous?

Lurking in the vast expanse of the ocean and buried deep in the Siberian permafrost, there are giants—not blue whales and mammoths, but giant viruses.

Cartoon illustration of dead, rod-shaped bacteria, signifying Mycobacterium tuberculosis successfully defeated by antibiotics.

New “Kill Test” Could Help Screen Better Antibiotics

A new single cell-based screening tool evaluates how well antibiotics kill bacteria and may help researchers determine which drugs perform best in patients.

Multimedia

Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

In this webinar, scientists will discuss innovations that are unlocking new insights into immunity.

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

In this webinar, Magdalena Pacewicz will highlight how to use AUC to characterize AAVs as part of ensuring regulatory compliance.

Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.

January 2026

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue

Research Resources

Podcasts

Webinars

Videos

Infographics

eBooks

Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

In this webinar, scientists will discuss innovations that are unlocking new insights into immunity.

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

In this webinar, Magdalena Pacewicz will highlight how to use AUC to characterize AAVs as part of ensuring regulatory compliance.

Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

In this webinar, Andre Mueller will discuss how scientists characterize therapeutic proteins in different formulations and spot the effects of excipients on protein stability.

Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

A streamlined, automated process helps scientists coordinate site-ready production-level whole genome sequencing results.

Products

Product News

Nuclera eProtein Discovery System installed at leading Universities in Taiwan

System strengthens Taiwan’s capabilities in protein drug discovery research

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

The Transferpette® pro expands the Transferpette® family, offering scientists even greater flexibility to match their pipetting preferences and workflow requirements.

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Fast, gentle, and highly specific glycoprotein labeling compatible with downstream immunofluorescence, enabled by next-generation aminooxy chemistry.

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Scientific X and S Series General Purpose Centrifuges are designed to help provide exceptional performance, versatility and enhanced sustainability.