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Rapidly Dividing Bacteria Coordinate Gene Expression and Replication
Rapidly Dividing Bacteria Coordinate Gene Expression and Replication
E. coli divides faster than it can replicate its genome, while simultaneously expressing its genes. Scientists recently revealed the intricate molecular coordination that makes this possible.
E. coli divides faster than it can replicate its genome, while simultaneously expressing its genes. Scientists recently revealed the intricate molecular coordination that makes this possible.
gene regulation
Viral Protein Behind Chronic Inflammation in People with HIV: Study
Natalia Mesa, PhD | Dec 12, 2022 | 3 min read
The HIV protein Nef can cause long-term genetic changes that lead to hyperreactive immune cells, according to research in human cells and mice.
Epigenetics May Remember Ancestors’ Mutations
Holly Barker, PhD | Dec 1, 2022 | 4 min read
Parents’ mutations, even if they’re not inherited by offspring, could affect subsequent generations through changes to epigenetic marks, a study finds.
Advancing Drug Discovery by Employing Synthetic Biology Tools
The Scientist | 1 min read
In this webinar, learn about the origins of artificial gene circuits and how researchers currently use synthetic biology strategies to uncover new drugs.
X Chromosome Silenced in Some Cancers in Males
Natalia Mesa, PhD | Nov 11, 2022 | 3 min read
A study finds that XIST, the gene that shuts down one X chromosome in people who have two, is linked to cancer in males.
Katharina Höfer Probes the Machinery of Bacterial Gene Expression
Hannah Thomasy, PhD | Jun 13, 2022 | 3 min read
The molecular biologist studies how chemical modifications to RNA building blocks change the way RNA regulates complex cellular processes.
The Scientist's Journal Club: Transcriptomics
The Scientist | 2 min read
Scientists discuss their latest findings on immune cell dynamics, neurodegenerative disease risk factors, and rare cell types obtained from bulk and single cell RNA sequencing experiments.
Same RNA Acts in Neurodegeneration and Cancer
Abby Olena, PhD | Oct 29, 2021 | 3 min read
The long noncoding RNA MINCR, implicated in ALS and Alzheimer’s disease as well as several types of cancer, appears to function differently when present at high versus low levels.
Signaling Dynamics Fine-Tune Gene Expression
Ruth Williams | Sep 3, 2021 | 3 min read
The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.
Technique Talk: The Inside Scoop on Successful ATAC-seq Experiments
The Scientist | 1 min read
Discover how to best map a cell’s epigenetic landscape
Gene Offers Clue to How Human Labor Starts
Christie Wilcox, PhD | Aug 1, 2021 | 2 min read
Genes associated with preterm birth and protecting the fetus from the mother’s immune system appear to be regulated by HAND2.
How Early-Morning Light Exposure Makes Mice Less Depressed
Bianca Nogrady | Jul 22, 2021 | 4 min read
A light-sensitive gene involved in regulating the body clock may also influence mood, mediating the effect of light.
Bridging the Gap: Integrating Single-Cell Transcriptomics and Proteomics
The Scientist Creative Services Team in Collaboration with IsoPlexis | 1 min read
An expert panel will discuss how a functional cell library confirms critical insights from previous omics studies. Additionally, they will introduce an innovative platform that connects single cell transcriptomics with functional proteomics for the first time.
Cancer May Be Driven by DNA Outside of Chromosomes
Paul Mischel | Apr 1, 2021 | 10+ min read
In the last decade, researchers have come to realize that tumors harbor bits of extrachromosomal DNA that can drive malignancy.
Infographic: The Role of Extrachromosomal DNA in Cancer
Paul Mischel | Apr 1, 2021 | 2 min read
Researchers are uncovering how circular bits of DNA found in some cancer cells can help tumors evolve and kill.
Sample Preparation with Single Cell Multiomics: Simultaneous Epigenomic and Transcriptomic Profiling from the Same Cell
The Scientist | 1 min read
In this webinar brought to you by 10x Genomics, experts will discuss how to successfully prepare nuclei suspensions for Single Cell Multiome ATAC + Gene Expression experiments.
Regulators of Gene Activity in Animals Are Deeply Conserved
Amanda Heidt | Nov 6, 2020 | 5 min read
Enhancers, short regions of DNA that direct gene expression, of species separated by 700 million years of evolution worked interchangeably, according to a new study.
New Map Charts Genetic Expression Across Tissue Types, Sexes
Ashley Yeager | Sep 10, 2020 | 3 min read
A decade-long effort to probe gene regulation reveals differences between males and females, points to essential regulatory elements, and offers insight into past work on telomeres.
Getting Started with Single Cell Multiomics: Simultaneous Epigenomic and Transcriptomic Profiling from the Same Cell
The Scientist | 1 min read
In this webinar brought to you by 10x Genomics, experts will discuss tips for running Chromium Single Cell Multiome ATAC + Gene Expression experiments in your lab.
Cracking Down on Cancer: A Profile of Owen Witte
Diana Kwon | Apr 1, 2020 | 9 min read
Through his studies on cancer-causing viruses, the University of California, Los Angeles, professor has helped develop lifesaving treatments.