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| 4 min read
Base editing corrected a mutation that causes macular degeneration, highlighting the potential of gene therapy to treat ocular diseases.

gene therapy

Explore a Concise Guide to Optimizing Viral Transduction

A Visual Guide to Lentiviral Gene Delivery

Takara Bio
3D illustration of a gold lipid nanoparticle with pink nucleic acid inside of it. Purple and teal spikes stick out from the lipid bilayer representing polyethylene glycol.

A Nanoparticle Delivery System for Gene Therapy

Crystal structure of adeno-associated virus serotype 3B

A Deep Dive into Viral Vectors for Gene Therapy 

Polyplus logo
Improving Gene Therapy Safety with Antibiotic- and Supplement-Free Mini Plasmids

Improving Gene Therapy Safety with Antibiotic- and Supplement-Free Mini Plasmids

VectorBuilder
Two hands holding tweezers and dissecting single points in a DNA sequence.

From CRISPR to Prime Editing: The Evolution of the Genome Editing Revolution

Abstract, colorful illustration of the human brain

A Gene Therapy to Treat the FOXG1 Brain Disorder 

An illustration of orange, blue, and grey lentiviral particles on a white background.

Scaling Up Lentiviral Vector Manufacturing 

Thermo Fisher Logo
An artist’s representation of the human respiratory system with pink airways on a blue and black background.

A Gene Editing System Corrects Cystic Fibrosis Mutation

An illustration of an adeno-associated virus.

Streamlining Viral Gene Therapy Development

Charles River Laboratories, Inc logo
Conceptual vector image of scientist engage in molecular biology research.

Helper Plasmids Lend a Hand to AAV Production

Polyplus logo
Pharmaceutical manufacturing facility

GMP-Grade Streamlines Cell and Gene Therapy Manufacturing

Acro 
iStock

Catch Me If You Can: Sequencing Screens for Rare Disease Genes

Velsera Logo
Conceptual gene therapy illustration with 3D multicolored adeno-associated viruses in the foreground and multicolored DNA strands in the background.

Quality Control for Cell and Gene Therapy

Bio-Rad
Bringing Gene Therapy to the Brain

Bringing Gene Therapy to the Brain

An abstract illustration of a DNA helix and human lungs.

A New Delivery System Offers Hope for Cystic Fibrosis

Molecular illustration of CRISPR editing the DNA double helix

Prime Time Precision with CRISPR Technologies

Different colored cartoon viruses entering holes in a cartoon of a human brain.

A Journey Into the Brain

DNA molecule.

Finding DNA Tags in AAV Stacks

Genotoxic Effects of Base and Prime Editing

Conceptual colorful illustration of scientists working with bioreactors and other laboratory equipment.

Next-Level Adeno-Associated Virus (AAV) Production 

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Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

An illustration of mustard-colored mitochondria against a dark blue background.

Mitochondrial DNA: A Maternal Legacy That Helps Trace the Past and Diagnose the Future

A blue gloved hand holding several vials on a black background.

A Man Who Survived Hundreds of Snakebites Helped Scientists Develop a Potent Antivenom

Photo of a woman submerged in icy water with her head and clasped hands above water.

What are the Risks and Benefits of a Cold Plunge?

Multimedia

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Bio-Rad
Exploring the Gut-Lung Axis in Health and Disease

Exploring the Gut-Lung Axis in Health and Disease

May digest 2025 cover
May 2025, Issue 1

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

View this Issue
Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Bio-Rad
How technology makes PCR instruments easier to use.

Making Real-Time PCR More Straightforward

Thermo Fisher Logo
Characterizing Immune Memory to COVID-19 Vaccination

Characterizing Immune Memory to COVID-19 Vaccination

10X Genomics
Optimize PCR assays with true linear temperature gradients

Applied Biosystems™ VeriFlex™ System: True Temperature Control for PCR Protocols

Thermo Fisher Logo

Products

Leica Microsystems Logo

Latest AI software simplifies image analysis and speeds up insights for scientists

BioSkryb Genomics Logo

BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours

iStock

Agilent BioTek Cytation C10 Confocal Imaging Reader

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Sapio Sciences logo

Sapio Sciences Introduces Biorepository Management Solution