Crystal structure of adeno-associated virus serotype 3B
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As the demand for viral vectors rises in new gene therapy approaches, scientists seek ways to optimize their production.

gene therapy

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A Gene Therapy to Treat the FOXG1 Brain Disorder 

An illustration of orange, blue, and grey lentiviral particles on a white background.

Scaling Up Lentiviral Vector Manufacturing 

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An artist’s representation of the human respiratory system with pink airways on a blue and black background.

A Gene Editing System Corrects Cystic Fibrosis Mutation

An illustration of an adeno-associated virus.

Streamlining Viral Gene Therapy Development

Charles River Laboratories, Inc logo
Conceptual vector image of scientist engage in molecular biology research.

Helper Plasmids Lend a Hand to AAV Production

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Pharmaceutical manufacturing facility

GMP-Grade Streamlines Cell and Gene Therapy Manufacturing

Acro 
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Catch Me If You Can: Sequencing Screens for Rare Disease Genes

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Conceptual gene therapy illustration with 3D multicolored adeno-associated viruses in the foreground and multicolored DNA strands in the background.

Quality Control for Cell and Gene Therapy

Bio-Rad
Bringing Gene Therapy to the Brain

Bringing Gene Therapy to the Brain

An abstract illustration of a DNA helix and human lungs.

A New Delivery System Offers Hope for Cystic Fibrosis

Molecular illustration of CRISPR editing the DNA double helix

Prime Time Precision with CRISPR Technologies

Different colored cartoon viruses entering holes in a cartoon of a human brain.

A Journey Into the Brain

DNA molecule.

Finding DNA Tags in AAV Stacks

Genotoxic Effects of Base and Prime Editing

Conceptual colorful illustration of scientists working with bioreactors and other laboratory equipment.

Next-Level Adeno-Associated Virus (AAV) Production 

Abstract illustration depicting coronavirus research concept.

Curiosity and Compassion Fuel Rare Disease Research

The Wonderfully Shrunken Cas13

Illuminating Organs with Organoids

Illuminating Organs with Organoids

Lipid nanoparticle

Which Gene Therapy Delivery Vector Will Emerge Victorious? 

A man sitting at a desk in a white lab coat holds up a large model of a <em >Drosophila</em> fly. In the background is a window and a bookcase.

The Origins and Recent Promise of Nonsense Suppressor tRNAs

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A Common Plastic Additive Harms DNA and Chromosomes

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Why Does Geosmin Smell?

A histological cross-section of human skin, with a brown epidermis and pink dermis containing several, short, navy blue, wavy structures.&nbsp;

Sole Fibroblasts Injected into Thighs Help Develop a Thicker Skin

An illustration showing an internal view of the intestine with the gut microbiota.

Gut Bacteria Boost Levels of Sex Hormones with the Help of Flatulence

Multimedia

Innovative CRISPR Applications

Innovative CRISPR Applications

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Leveraging PCR for Rapid Sterility Testing

TS Digest January 2025
January 2025, Issue 1

Why Do Some People Get Drunk Faster Than Others?

Genetics and tolerance shake up how alcohol affects each person, creating a unique cocktail of experiences.

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Sex Differences in Neurological Research

Sex Differences in Neurological Research

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New Frontiers in Vaccine Development

New Frontiers in Vaccine Development

Sino
New Approaches for Decoding Cancer at the Single-Cell Level

New Approaches for Decoding Cancer at the Single-Cell Level

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Learn How 3D Cell Cultures Advance Tissue Regeneration

Organoids as a Tool for Tissue Regeneration Research 

Acro&nbsp;

Products

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Sapient Partners with Alamar Biosciences to Extend Targeted Proteomics Services Using NULISA™ Assays for Cytokines, Chemokines, and Inflammatory Mediators

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Bio-Rad Extends Range of Vericheck ddPCR Empty-Full Capsid Kits to Optimize AAV Vector Characterization

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Leveraging PCR for Rapid Sterility Testing

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Understanding the Nuts and Bolts of qPCR Assay Controls 

Bio-Rad