Graphic representing a team of scientists, clinicians, and drug manufacturers working together to build a CRISPR therapy

| 5 min read

How Teamwork Built a Customized CRISPR Gene Therapy

Mark Wetzel from Aldevron highlights how rapid, tailored gene-editing treatments could transform care for rare diseases.

AAV Avenues for Cell and Gene Therapy

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AAV Avenues for Cell and Gene Therapy

DNA molecules intertwined with pills, symbolizing CRISPR therapies and advances in modern medicine.

| 9 min read

CRISPR Therapy Progress and Prospects

gene therapy

Petros Giannikopoulos (right) and Fyodor Urnov (left) stand in the lab where the on-demand CRISPR therapy was produced. They are both wearing blue shirts and glasses.

Baby KJ’s Bespoke Gene Therapy Is a Masterclass in Scientific Collaboration

Rebecca Roberts, PhD | | 5 min read

Image of an adult mouse with a litter of baby mice.

Newborn Mice May Hold the Key to Simpler Gene Therapy

Laura Tran, PhD | | 3 min read

A cross-section showing blue, white, and green-colored cells against a black background.

Correcting the Mutation Behind a Genetic Eye Disease

Sneha Khedkar | | 4 min read

Illustration of two TALENs bound to DNA. Repetitive helices wrap around DNA and bind at dedicated sites in each repeat. An enzymatic nuclease domain attached to each TALEN allows for cutting of one strand of the DNA.

A Tale of How TALENs Launched the Genome Editing Revolution

Shelby Bradford, PhD | | 10 min read

Scaling Lentiviral Vector Manufacturing for Optimal Productivity

Thermo Fisher Scientific | | 1 min read

Explore a Concise Guide to Optimizing Viral Transduction

A Visual Guide to Lentiviral Gene Delivery

Takara Bio | | 1 min read

3D illustration of a gold lipid nanoparticle with pink nucleic acid inside of it. Purple and teal spikes stick out from the lipid bilayer representing polyethylene glycol.

A Nanoparticle Delivery System for Gene Therapy

Shelby Bradford, PhD | | 2 min read

Crystal structure of adeno-associated virus serotype 3B

A Deep Dive into Viral Vectors for Gene Therapy

PolyplusandThe Scientist | | 1 min read

Improving Gene Therapy Safety with Antibiotic- and Supplement-Free Mini Plasmids

Improving Gene Therapy Safety with Antibiotic- and Supplement-Free Mini Plasmids

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Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

Image of a collage with human hands working with desktop icons in a collage style.

q.e.d: An AI Tool for Smarter Manuscript Review

A team of researchers developed q.e.d, an AI-powered system designed to deliver rigorous and constructive feedback on scientific manuscripts in minutes.

An enveloped virus forms.

Where Do Viruses Come From?

Using genomics, evolutionary biologists test several hypotheses on the origin of viruses. New evidence suggests they may have emerged more times than previously thought.

A brown dog stares at a spoon of peanut butter in front of its face with wide eyes.

Why Do Dogs Love Peanut Butter?

The reason dogs beg, sit, stay, and shake for peanut butter could be both evolutionarily wired and learned behavior.

Multimedia

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

December digest cover image of a wooden sculpture comprised of multiple wooden neurons that form a seahorse.

December 2025, Issue 1

Wooden Neurons: An Artistic Vision of the Brain

A neurobiologist, who loves the morphology of cells, turns these shapes into works of art made from wood.

View this Issue

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Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Abstract wireframe sphere with colorful dots and connecting lines representing the complex cellular and molecular interactions within the tumor microenvironment.

Exploring the Inflammatory Tumor Microenvironment

Within the tumor microenvironment, networks of cells and molecular signals form a dynamic landscape that drives disease progression.

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A Comprehensive Guide to Next-Generation Sequencing

Individual NGS methods come with their own pros and cons, but automation optimization solutions exist for all NGS workflows.

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BRANDTECH® Scientific Announces Strategic Partnership with Copia Scientific to Strengthen Sales and Service of the BRAND® Liquid Handling Station (LHS)

This partnership will enable both companies to reach a broader range of customers, including those with more complex and specialized workflows

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Enter Our 2026 Top Innovations Contest

Submit a cutting-edge product or technology for the chance to be recognized as one of The Scientist’s 2026 Top Innovations.

Biotium Expands Tyramide Signal Amplification Portfolio with Brighter and More Stable Dyes for Enhanced Spatial Imaging

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LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS

Ten-year Agreement to Provide a Secure, AI-enabled Forensic Laboratory Information Management System Supporting DHS Forensic, Scientific, and Testing Services