hemoglobin

Makio Murayama, a Japanese-American biochemist who was turned away from the Manhattan Project due to his heritage, rose to prominence for his work uncovering the link between the structure of hemoglobin and the mechanisms of sickle cell disease.

New research finds that the appearance of the HbS mutation, which protects against malaria but leads to sickle cell disease when present in two copies, was more common in sperm samples from men in Ghana, where malaria risk is high, than Europeans.

By unraveling the molecular underpinnings of inherited blood disorders, the Boston Children’s Hospital researcher has provided the basis for therapies now being tested for beta-thalassemia and sickle cell disease.

Researchers discover anti-malarials called quinolones can halt the development of the parasites, offering a potential therapeutic avenue.

Researchers say they have sufficient in vitro and animal data to apply for human testing.

Diverse genetic changes lead to remarkably similar hemoglobin adaptations of diverse bird species, a study finds. 

Once implanted in mice, the edited stem cells produced normal hemoglobin.

Artemisinin targets multiple parasite proteins after being activated by the iron in heme cofactors.

Scientists use the genome-editing technique to fix a disease-causing mutation in human cell lines.

A review study indicates that clamping umbilical cords immediately after birth, rather than waiting a few minutes, may increase the risk of iron and hemoglobin deficiency in infants.

Some question the supposition that viable cells and DNA will be found in a remarkably preserved carcass, purported to harbor fresh muscle tissue and flowing blood.