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3D illustration of T cell attached to protein
“Smarter” CAR T Cells Target Tumors with Precision
Two studies in mice now show that researchers can control when and where CAR T cells are active, potentially overcoming previous hurdles for CAR T–based treatments.
“Smarter” CAR T Cells Target Tumors with Precision
“Smarter” CAR T Cells Target Tumors with Precision

Two studies in mice now show that researchers can control when and where CAR T cells are active, potentially overcoming previous hurdles for CAR T–based treatments.

Two studies in mice now show that researchers can control when and where CAR T cells are active, potentially overcoming previous hurdles for CAR T–based treatments.

interleukin
Illustration of HIV virus
Viral Protein Behind Chronic Inflammation in People with HIV: Study
Natalia Mesa, PhD | Dec 12, 2022 | 3 min read
The HIV protein Nef can cause long-term genetic changes that lead to hyperreactive immune cells, according to research in human cells and mice. 
A small, brown mouse runs on a narrow, miniature treadmill
How Exercise Helps Mice Fight Pancreatic Cancer
Dan Robitzski | Jun 15, 2022 | 5 min read
A study reveals a molecular pathway linking exercise to an amped-up immune response to pancreatic cancer and greater responsiveness to treatment.
illustration of people of different genders and races
Does Biological Sex Influence COVID-19 Outcomes?
Annie Melchor | Nov 2, 2021 | 10 min read
It’s unclear whether differing odds of dying between men and women reflect inherent differences between male and female immune systems or differences rooted in gender norms.
Infographic: How Vaccines Train Innate Immunity
Shawna Williams | Nov 1, 2020 | 1 min read
A recent study elucidates some of the changes that occur in the body after inoculation with a tuberculosis vaccine.
T Cells and Neurons Talk to Each Other
Ashley Yeager | Oct 1, 2020 | 10+ min read
Conversations between the immune and central nervous systems are proving to be essential for the healthy social behavior, learning, and memory.
Special Report
covid-19 sars-cov-2 coronavirus pandemic immune response severity severe biomarkers prognostic predictor neutrophil monocyte myeloid cytokine interleukin
The Immune Hallmarks of Severe COVID-19
Katarina Zimmer | Sep 16, 2020 | 10+ min read
Researchers are trying to make sense of immune systems gone haywire and develop biomarkers to predict who will become the sickest from a coronavirus infection.
Could Statins Reduce the Severity of COVID-19?
Ashley Yeager | Jun 12, 2020 | 7 min read
The cholesterol-lowering drugs quell inflammation and reverse endothelial tissue damage, hints that they might curb the body’s excessive immune response to SARS-CoV-2 infection.
Infographic: Exercise’s Anticancer Mechanisms
Bente Klarlund Pedersen | Apr 1, 2020 | 2 min read
A look at the molecular processes that may feed into the tumor-fighting effects of physical activity
Image of the Day: Gut Reaction
Carolyn Wilke | Feb 4, 2019 | 1 min read
Immune cells in the mouse gut help recognize damaging compounds and prompt intestinal stem cells to repair DNA.
Activating Beige Fat
Kerry Grens | Jun 5, 2014 | 3 min read
An innate immune pathway stimulates the activity of heat-producing adipose tissue in mice.
Molecular Multitasking
Carina Storrs | Aug 1, 2013 | 6 min read
Commercial kits use fluorescent beads to probe dozens of cytokines in one reaction.
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