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Tuning T Cells
An often overlooked property of the tumor environment shapes T cell function and may improve T cell therapies.
Tuning T Cells
Tuning T Cells

An often overlooked property of the tumor environment shapes T cell function and may improve T cell therapies.

An often overlooked property of the tumor environment shapes T cell function and may improve T cell therapies.

mechanotransduction

Nucleus Is Key to How Cells Sense Personal Space
Abby Olena, PhD | Oct 15, 2020 | 4 min read
In two independent studies, researchers find that the organelle is responsible for a switch that allows cells to start moving when they’re squeezed.
The Biggest Science News of 2018
Kerry Grens | Dec 27, 2018 | 7 min read
From disastrous scientific setbacks to the upending of scientific dogma and the end of a 40-year search for a protein
Long-Sought Hearing Channel Protein Found
Abby Olena, PhD | Aug 22, 2018 | 3 min read
After a decades-long pursuit, researchers have confirmed the identity of the pore of the mechanotransduction channel in vertebrates’ inner ear hair cells.
Hearing Channel Components Mapped
Kerry Grens | Sep 4, 2015 | 2 min read
Localization of two proteins important for inner ear hair cell function suggests they are part of the elusive mechanotransduction channel. 
Human Hearing: A Primer
The Scientist | Sep 1, 2015 | 1 min read
How the human ear translates sound waves into nervous impulses
Hearing Discrepancy Probed
Amanda B. Keener | Sep 1, 2015 | 3 min read
Common in vitro experiments have distorted the true mechanics of mammalian hair cell stereocilia.
Huh?
The Scientist | Aug 31, 2015 | 1 min read
Hearing loss can occur for a variety of reasons, and sometimes more than one.
Gene Therapy Fixes Mouse Hearing
Kerry Grens | Jul 9, 2015 | 1 min read
Expressing a gene for a component of the inner ear’s hair cells treated a form of genetic deafness.
Tricky Transfections
Ruth Williams | Mar 1, 2015 | 2 min read
A combination of microinjection and electroporation inserts genes into hard-to-reach cells.
New Piece of a Mysterious Channel
Kerry Grens | Nov 25, 2014 | 3 min read
Researchers have nailed down yet another component of the mechanotransduction complex responsible for relaying signals from hair cells in the ear.
Sensing a Little Tension
Nicholette Zeliadt | Sep 1, 2013 | 8 min read
Tools and techniques for measuring forces in living cells
Grading on the Curve
Edyta Zielinska | Jun 1, 2012 | 2 min read
Actin filaments respond to pressure by forming branches at their curviest spots, helping resist the push.
A Channel at Large
Kerry Grens | Nov 1, 2007 | 10 min read
A Channel at Large What is the mechanotransduction channel in hearing that has evaded scientists for decades? 
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