Gene Editing Treats Mitochondrial Disorders in Mice
Gene Editing Treats Mitochondrial Disorders in Mice
Researchers used TALENs and zinc finger nucleases to correct disease-causing mutations.
Gene Editing Treats Mitochondrial Disorders in Mice
Gene Editing Treats Mitochondrial Disorders in Mice

Researchers used TALENs and zinc finger nucleases to correct disease-causing mutations.

Researchers used TALENs and zinc finger nucleases to correct disease-causing mutations.

Mitochondrial disease
Mitochondrial Isolation System
Mitochondrial Isolation System
Ruth Williams | May 1, 2018
A transgenic approach allows researchers to collect the organelles from specific cells in nematodes with unprecedented efficiency.
Infographic: Isolating mitochondria from specific cell types
Infographic: Isolating mitochondria from specific cell types
Ruth Williams | May 1, 2018
Adding a fusion gene to certain mitochondria in C. elegans enables researchers to collect and analyze them.
Image of the Day: Mitochondria, Live and in Color
Image of the Day: Mitochondria, Live and in Color
The Scientist Staff | Sep 27, 2017
Mitochondria age differently depending upon whether they’re located in the liver, heart, or kidney, scientists find in flies and mice.
Details of First Three-Parent IVF Revealed
Details of First Three-Parent IVF Revealed
Bob Grant | Apr 3, 2017
The team that oversaw the first use of mitochondrial replacement therapy that resulted in a live birth has published an account of the procedure.
Opinion: Ethical Considerations of “Three-Parent” Babies
Opinion: Ethical Considerations of “Three-Parent” Babies
John D. Loike and Nancy Reame | Dec 22, 2016
Mitochondrial replacement therapy raises important societal and ethical concerns, but should be embraced for its utility in preventing disease.
Three-Parent IVF Advances
Three-Parent IVF Advances
Anna Azvolinsky | Nov 30, 2016
Differences in the replicative advantages conferred by some mitochondrial DNA haplotypes have implications for mitochondrial replacement therapy, researchers report. 
Kids’ Sudden Cardiac Deaths Explained by Heritable Mutations in a Single Gene
Kids’ Sudden Cardiac Deaths Explained by Heritable Mutations in a Single Gene
Kerry Grens | Aug 11, 2016
Examining the tragedies of several families who each lost multiple children, two teams of researchers reveal a previously unappreciated role for a mitochondrial enzyme.
Improving Mitochondrial Replacement Therapy
Improving Mitochondrial Replacement Therapy
Anna Azvolinsky | Jun 8, 2016
Pronuclear transfer can reduce the risk of transferring defective mitochondria, a study shows.  
Bill Banning Mitochondrial Replacement Therapy Considered
Bill Banning Mitochondrial Replacement Therapy Considered
Tanya Lewis | May 19, 2016
The US Senate is reviewing a bill that would extend a ban on so-called three-parent embryos.