The recent discovery of 17 people who have inherited maternal and paternal lines of mitochondrial DNA has major ramifications for medical and ancestry research.

Researchers identify unique cases in which people inherited mitochondrial DNA not just from their mother but also from their father.

Researchers used TALENs and zinc finger nucleases to correct disease-causing mutations.

A transgenic approach allows researchers to collect the organelles from specific cells in nematodes with unprecedented efficiency.

Adding a fusion gene to certain mitochondria in C. elegans enables researchers to collect and analyze them.

Mitochondria age differently depending upon whether they’re located in the liver, heart, or kidney, scientists find in flies and mice.

The team that oversaw the first use of mitochondrial replacement therapy that resulted in a live birth has published an account of the procedure.

Mitochondrial replacement therapy raises important societal and ethical concerns, but should be embraced for its utility in preventing disease.

Differences in the replicative advantages conferred by some mitochondrial DNA haplotypes have implications for mitochondrial replacement therapy, researchers report. 

Examining the tragedies of several families who each lost multiple children, two teams of researchers reveal a previously unappreciated role for a mitochondrial enzyme.

Pronuclear transfer can reduce the risk of transferring defective mitochondria, a study shows.  

The US Senate is reviewing a bill that would extend a ban on so-called three-parent embryos.

Experts from the US National Institute of Medicine outline their conditional approval of clinical research on mitochondrial replacement techniques.

Researchers generate patient-specific induced pluripotent stem cells corrected for mitochondrial defects.

And too few insights gleaned from them

Researchers develop a method to selectively remove mutated mitochondrial DNA from the murine germline and single-celled mouse embryos.

Research reveals how the brain changes as we age and hints at ways to slow the decline.

Parliament today voted to allow techniques that could help couples produce babies with a reduced chance of passing on heritable mitochondrial diseases.

Pathogenic mutations in mitochondrial DNA are common in healthy people, according to a new study.