mutation

Illustration of SARS-CoV-2

US Agency to Look into Project on Modified Coronavirus

Illustration of pink and blue DNA molecules.

Historic Adaptations May Now Make Us Susceptible to Disease

Illustration of a human and Neanderthal skull side by side.

Mutation Linked to Difference Between Human and Neanderthal Brains

Brown coral in shallow water branching upward with blue fish in front. 

Corals Upend Longstanding Idea About Genetic Inheritance

To flag neurons that have experienced genotoxic stress, researchers developed an in vivo sensor using an adeno-associated viral vector, called PRISM. Because a cell’s DNA damage response (DDR)—which activates in response to stressors such as environmental toxins or the buildup of misfolded proteins—also responds to invading pathogens, PRISM has an easier time transfecting cells whose damage response mechanisms are preoccupied with existing DNA damage. Once inside, the virus hijacks the neuron’s DNA replication machinery, which reverts an engineered frameshift mutation in the virus and thereby prompts the production of a fluorescent protein that can be observed via microscopy.

Infographic: DNA Damage Viewed with Unprecedented Clarity

Broken DNA

DNA Damage Viewed with Unprecedented Clarity

Artist’s rendition of a blue-green DNA double helix, viewed lengthwise from within one end.

Stem Cell Lines Riddled With Undetected Mutations

Artist&rsquo;s rendition of multiple <em>Neisseria gonorrhoeae</em>, the bacteria that causes gonorrhea, depicted as two spheres stuck together, each covered in tendrils.

Gonorrhea-Blocking Mutation Also Protects Against Alzheimer’s: Study

The Mosaic Brain

multicolor DNA sequencing gel

Genetic Mutations Can Be Benign or Cancerous—a New Method to Differentiate Between Them Could Lead to Better Treatments

Illustration of light blue speckled DNA helix on a dark background

Study Nearly Doubles Known Cancer-Linked Mutational Signatures

Microscopy image showing patches of magenta and green

Three Autism-Linked Genes Converge on Tweaks to Cells’ Timing

Trending

An old medical illustration features the ear in the center with nerves of the head shown in yellow.

The Ear as a Therapeutic Gateway to the Vagus Nerve

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

3D illustration showing three differently colored semi-translucent cells, representing different T cell subtypes, on a black background. A purple cell is in the front on the right, a red cell is on the left, and a blue cell sits behind the red one.

T Cell Nomenclature Gets an Update

A yellow-colored frozen frog.

Freeze-Tolerant Frogs Power Organ Cryopreservation Strategies

Multimedia

Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

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Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

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Products

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BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

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Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

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VANTAstar Flexible microplate reader with simplified workflows

BMG LABTECH