Mouse Immune Cells Destroy Nerves’ Coating, Causing Chronic Pain
Mouse Immune Cells Destroy Nerves’ Coating, Causing Chronic Pain
A study suggests a way in which acute nerve injury could trigger an autoimmune response that leads to continuing pain in mice.
A study suggests a way in which acute nerve injury could trigger an autoimmune response that leads to continuing pain in mice.
neuroimmunology
Mouse Study Suggests Fibromyalgia Has Autoimmune Roots
Annie Melchor | Jul 2, 2021 | 2 min read
When researchers injected mice with antibodies from fibromyalgia patients, the animals developed symptoms of the disease—suggesting that it may be controlled by the immune system, not the nervous system.
A Tweak to Immune Cells Reverses Aging in Mice
Abby Olena, PhD | Jan 20, 2021 | 3 min read
Knocking out the receptor for a lipid that causes inflammation rejuvenates macrophage metabolism and restores cognitive function in an Alzheimer’s disease model.
Zika Linked to More Neurological Problems in Adults
Kerry Grens | Aug 14, 2017 | 2 min read
A review of several dozen hospitalized patients in Brazil finds neurological conditions, including inflammation of the brain and spinal cord, in addition to Guillain-Barre syndrome.
Immune Cells Deliver Cancer Drugs to the Brain
Diana Kwon | Jun 19, 2017 | 3 min read
Neutrophils loaded with the chemotherapy drug paclitaxel traverse the blood-brain barrier and kill residual cancer cells after tumor-resection surgery in mice.
Image of the Day: Long-Distance Messaging
The Scientist | Apr 6, 2017 | 1 min read
After an inflammatory injury occurs in the brain, astrocytes release extracellular vesicles that travel to the liver and trigger an immune response.
Immune System Maintains Brain Health
Amanda B. Keener | Nov 1, 2016 | 10+ min read
Once thought only to attack neurons, immune cells turn out to be vital for central nervous system function.
From Body to Brain
The Scientist | Oct 31, 2016 | 1 min read
Researcher Michal Schwartz discusses the promise of neuroimmunology to treat neurological disease.
Immunity in the Brain
Amanda B. Keener | Oct 31, 2016 | 2 min read
Researchers document the diverse roles of immune cells in neuronal health and disease.
Sex Differences in Pain Pathway
Amanda B. Keener | Jun 29, 2015 | 4 min read
Male and female mice utilize different immune cells to process pain, a study shows.
Targeted Brain Cancer Vaccine
Anna Azvolinsky | Jun 25, 2014 | 3 min read
Mouse study demonstrates the ability of a cancer vaccine targeted against a specific oncogenic mutation to elicit a protective anti-tumor immune response.
Viruses on the Brain
Beth Marie Mole | May 1, 2013 | 2 min read
Viral infections of the central nervous system may trigger cytokines that induce seizures.
Can Worms Alleviate Autism?
Sabrina Richards | Nov 27, 2012 | 3 min read
Autism researchers are testing the ability of whipworm eggs to treat autism in a new clinical trial.
Immune Role in Brain Disorder?
Hannah Waters | Mar 19, 2012 | 3 min read
Replacing immune cells in a mouse model of Rett syndrome, a developmental brain disorder, improved symptoms, suggesting a new target for treatment.
Top 7 in Neuroscience
Edyta Zielinska | Nov 8, 2011 | 3 min read
A snapshot of the most highly ranked articles in neuroscience and related areas, from Faculty of 1000
Blood’s Role in the Aging Brain
Edyta Zielinska | Aug 31, 2011 | 3 min read
A blood protein involved in allergy contributes to the decline in brain function and memory in aging mice.
Foresight
Karen Hopkin | Jul 1, 2011 | 9 min read
Studying the earliest events in visual development, Carla Shatz has learned the importance of looking at one’s data with open eyes—and an open mind.