Engineered Plasmodium parasites form the basis of two experimental malaria vaccines that showed safety and encouraging immune responses in clinical trials.

Two studies show that Plasmodium—the genus of protozoans that cause malaria—have an internal sense of time that synchronizes with their host’s circadian rhythms and allows the parasites to collectively attack blood cells.

The Duke University professor studies the parasite to find a way to thwart infection before it takes hold.

The physiological changes that can occur in the retinas of patients with cerebral malaria may provide a useful approach to diagnosis.

The microbiologist’s research led to the development of the first human malaria vaccine.

Researchers identified a gene in mosquitoes that moderates their susceptibility to malaria parasite infection. 

After discovering a novel organelle found in protozoan parasites, the University of Pennsylvania’s Roos created a widely used eukaryotic pathogen database.

Rather than providing complete protection, the long-awaited vaccine merely delays infection by a few years, scientists show.

Up to one-quarter of the US white-tailed deer population may harbor a Plasmodium parasite, a study shows.

Using the precision gene-editing tool, researchers demonstrate an ability to create large populations of malaria parasite–resistant mosquitoes.

Researchers identify mutations associated with resistance to the frontline antimalarial drug artemisinin.

What researchers are learning as they sequence, map, and decode species’ genomes