T cell receptor

By editing primary T cells with CRISPR, researchers begin to settle a long-standing debate about a common autoimmunity risk variant.

Havran described gamma-delta T cells’ direct function in epithelial repair.

The Oxford researcher’s work on lipid and peptide antigens revealed key mechanisms in inflammation, immunotherapy, and vaccination, which are being pursued in clinical trial treatments.

Human naive T cells are far more heterogeneous than has long been appreciated, having implications for vaccine strategies.

Neoantigens may serve as valuable targets for new immunotherapies.