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Infographic: Understanding CAR-T vs TCR Approaches
Living drugs get a boost from emerging engineering strategies that focus on safety and specificity.
Infographic: Understanding CAR-T vs TCR Approaches
Infographic: Understanding CAR-T vs TCR Approaches

Living drugs get a boost from emerging engineering strategies that focus on safety and specificity.

Living drugs get a boost from emerging engineering strategies that focus on safety and specificity.

T cell receptor

3D Rendering of Molecular Interaction in CAR Chimeric Antigen Receptor
Next-generation CAR and TCR Cancer Therapies
Danielle Gerhard, PhD | Mar 15, 2024 | 10+ min read
From smart receptors to novel biologics, scientists plan to overcome the challenges of treating solid tumors.
3D illustration of a lymphocyte in white and green.
A Quest for the Holy Grail of Cancer Targets
Danielle Gerhard, PhD | Mar 14, 2024 | 5 min read
Christopher Klebanoff hopes that his search for a small fraction of cancer-specific antigens will have a big impact on cancer cell therapies.
Move Over, Proteins! Exploring Lipids in Adaptive Immunity
Kamal Nahas, PhD | Nov 27, 2023 | 5 min read
New research revealed hundreds of lipid antigens that may be recognized by adaptive immune T cells.
Explore How Adaptive Immune Receptor Repertoire Profiling Characterizes Immune Cells
Revealing Immune Responses with Adaptive Immune Receptor Repertoire Profiling
Cellecta, Inc. | Oct 19, 2023 | 1 min read
Immune receptor repertoire profiling is an important analytic tool for disease research in many areas, including cancer, cell and organ transplantation, autoimmunity, and infectious disease. 
Editing genome stock photo
Resolving Discrepancies in Mouse and Human Autoimmunity Studies
Niki Spahich, PhD | May 15, 2023 | 4 min read
By editing primary T cells with CRISPR, researchers begin to settle a long-standing debate about a common autoimmunity risk variant.
knitted pink heart with a mended hole
CAR T Cells Mend Broken Mouse Hearts
Sophie Fessl, PhD | Jan 6, 2022 | 4 min read
Specialized immune cells generated in vivo reduce cardiac scar tissue in mice, a new study shows.
Immunologist Wendy Havran Dies
Lisa Winter | Jan 28, 2020 | 3 min read
Havran described gamma-delta T cells’ direct function in epithelial repair.
Immunology Leader Vincenzo Cerundolo Dies
Ashley Yeager | Jan 16, 2020 | 2 min read
The Oxford researcher’s work on lipid and peptide antigens revealed key mechanisms in inflammation, immunotherapy, and vaccination, which are being pursued in clinical trial treatments.
Opinion: We Have Been Naive About Naive T Cells
Jos├ę A.M. Borghans, Femke van Wijk, and Theo van den Broek | Apr 6, 2018 | 3 min read
Human naive T cells are far more heterogeneous than has long been appreciated, having implications for vaccine strategies.
Infographic: Targeting Cancer Antigens
Stephen P. Schoenberger and Ezra Cohen | Mar 31, 2017 | 1 min read
Neoantigens may serve as valuable targets for new immunotherapies.
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