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Top 10 Innovations

Top Innovations

About the Top Innovations Contest

Every year since 2008, The Scientist has canvassed the life-science community to find out which newly released products are having the biggest impact on research. After collecting submissions from companies and individuals, we put the new innovations before a carefully selected panel of expert, independent judges. Our judges rank the tools, techniques, methodologies, software, and products according to their potential to foster rapid advances or address specific problems in their respective fields. The products that rate the highest in our judges’ opinions are then featured in multiple ways on The Scientist website, magazine, social media, and more. Our goal is to identify those products and services that are poised to revolutionize research and advance scientific knowledge. Please stay tuned to The Scientist to learn which products won spots in the Top Innovations contest this year.

Recent Features

The Scientist’s 2026 Top Innovations contest logo with a rocket ship coming out of a light bulb
| 3 min read
This year’s awardees represent cutting-edge technologies advancing basic research, biotechnology, healthcare, and beyond.

Past Top 10 Innovations

A space-filling model of a Cas12l nuclease.

Next-Generation CRISPR Nucleases Expand Therapeutic Options

Photo of Vireo

Accelerating Live-Cell Discovery with Parallel Imaging

A photo of the Haystack MRD® blood collection kit.

Detecting Rare Cancer Markers to Inform Patient Care

Photo of AVITI24

Assembling a Multiomic Symphony with 5D Analysis

A photo of the meCUT&RUN DNA methylation mapping assay within its box.

Redefining High-Resolution DNA Methylation Mapping

Photo of The Well-Watcher

An Instrument That Minimizes Pipetting Mistakes with Real-Time Tracking

A photo of the Countable PCR platform and reagents.

Single-Molecule Counting Unveils Accurate Nucleic Acid Data

An image of Takara Bio USA’s Lenti-X T-Cell Transduction Sponge, zooming in on its macropores and showing how T cells and viruses move through the sponge.

T Cell Engineering Takes Sponge-Based Shortcut

Photo of the Evercode WT Penta

A Technology that Scales Up Whole Transcriptome Single-Cell Analysis

Trending

A team of cartoon scientists studying a giant pancreas.

Prolonged GLP-1 Exposure Remodels Gene Expression in the Pancreas by Flipping a Molecular Switch

Image of a Diploptera punctata cockroach.

Cockroach Milk Proteins Churn Out an Ig Nobel Win

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A drawing of men and women holding boxes, resigning en mass from their jobs as editors.

Editors Mass Resign from Elsevier Journal After Editor-in-Chief Let Go

Multimedia

Essential Genes Are Dominantly Activated by Single Transcription Factors

Essential Genes Are Dominantly Activated by Single Transcription Factors

EpiCypher Logo
Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Alamar Biosciences logo
The Scientist Digest cover September 2026
September 2026

Multiplex Microscopy Becomes Easier with Encoded Antibodies

A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies.

View this Issue
Essential Genes Are Dominantly Activated by Single Transcription Factors

Essential Genes Are Dominantly Activated by Single Transcription Factors

EpiCypher Logo
Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Alamar Biosciences logo
Engineering CAR-Neutrophils In Vivo to Target Glioblastoma

Engineering CAR-Neutrophils In Vivo to Target Glioblastoma

Miltenyi
Best Practices for qPCR Assay Design and Optimization

Best Practices for qPCR Assay Design and Optimization

Bio-Rad

Products

Closeup image of a multi channel pipette dispensing pink liquid into a 96-well plate.

The ASSIST PLUS pipetting robot for affordable workflow automation

Integra Logo
Single cells in suspension

Rapidly isolate primary cells and make uniform single-cell suspensions with Corning® Cell Strainers

Corning logo
Abstract image representing cell membranes linked together.

CellBrite® Steady Membrane Stain: Cell surface staining built for real-time imaging

Biotium
sino biological logo

Monod Bio Licenses AI-designed Protein Technologies to SignalChem Biotech for Custom Discovery Assays