Fat Cells Send Mitochondrial Distress Signals to the Heart
Fat Cells Send Mitochondrial Distress Signals to the Heart
Vesicles containing fragments of the organelles released from stressed adipocytes protect the heart against oxygen deprivation, a study in mice shows.
Fat Cells Send Mitochondrial Distress Signals to the Heart
Fat Cells Send Mitochondrial Distress Signals to the Heart

Vesicles containing fragments of the organelles released from stressed adipocytes protect the heart against oxygen deprivation, a study in mice shows.

Vesicles containing fragments of the organelles released from stressed adipocytes protect the heart against oxygen deprivation, a study in mice shows.

vesicles
PD-L1 in Extracellular Vesicles May Help Glioblastoma Evade Immunotherapies
PD-L1 in Extracellular Vesicles May Help Glioblastoma Evade Immunotherapies
Jim Daley | Mar 8, 2018
The discovery suggests that the immune checkpoint can operate at a further distance from tumor cells than previously believed.
Neurons Use Virus-Like Proteins to Transmit Information
Neurons Use Virus-Like Proteins to Transmit Information
Diana Kwon | Jan 15, 2018
In mice and flies, the Arc protein forms capsids and carries genetic information.
Macrophages Physically Relay Signals Between Cell Types
Macrophages Physically Relay Signals Between Cell Types
Catherine Offord | May 1, 2017
Time-lapse imaging shows the immune cells transferring chemical signals during pigment pattern formation in developing zebrafish.
Infographic: How the Zebrafish Got Its Stripes
Infographic: How the Zebrafish Got Its Stripes
Catherine Offord | Apr 30, 2017
Immune cells called macrophages shuttle cellular messages in the skin.
Neuron Signaling Persists, Faintly, Even When Key Presynaptic Proteins Are Absent
Neuron Signaling Persists, Faintly, Even When Key Presynaptic Proteins Are Absent
Ben Andrew Henry | Nov 1, 2016
Results from experiments in mice revise a long-held hypothesis that certain protein scaffolds are needed for synaptic activity.
Palade Particles, 1955
Palade Particles, 1955
Kerry Grens | Feb 1, 2014
Electron microscopy led to the first identification of what would later be known as ribosomes.
Palade and His Particles
Palade and His Particles
Kerry Grens | Jan 31, 2014
Nobel Laureate Christian de Duve discusses the impact of George Palade’s work on ribosomes.
Microbes Expel Swarms of Vesicles
Microbes Expel Swarms of Vesicles
Kerry Grens | Jan 10, 2014
Scientists present the first evidence that marine cyanobacteria release vesicles—billions and billions of vesicles.
Week in Review: October 7–11
Week in Review: October 7–11
Jef Akst | Oct 11, 2013
Nobels awarded for vesicle trafficking and computational chemistry; building 3-D microbial communities; mislabeled microbes cause retractions
Vesicle Trafficking Trio Wins Nobel
Vesicle Trafficking Trio Wins Nobel
Kerry Grens | Oct 7, 2013
James Rothman, Randy Schekman, and Thomas Südhof share Nobel Prize in Medicine or Physiology.  
SNAREs at the Synapse
Megan Scudellari | Jul 1, 2012
Using tiny lipid discs, scientists resolve contradictory evidence about how many proteins are required for neurotransmitter release.
Cancer Exosomes Promote Metastasis
Jef Akst | May 29, 2012
Vesicles released by melanoma cells stimulate pro-metastasis behaviors in bone marrow cells.
How Autophagy Works
How Autophagy Works
Muriel Mari, Sharon A. Tooze, and Fulvio Reggiori | Feb 1, 2012
There are five steps of autophagosome biogenesis: induction, expansion, vesicle completion, fusion, and cargo degradation. 
The Enigmatic Membrane
Muriel Mari, Sharon A. Tooze, and Fulvio Reggiori | Feb 1, 2012
Despite years of research, the longstanding mystery of where the autophagosome gets its double lipid bilayers is not much clearer.
Traffic Cops
Jessica P. Johnson | Oct 1, 2011
Editor's Choice in Cell Biology
Exosome Explosion
Exosome Explosion
Clotilde Théry | Jul 1, 2011
These small membrane vesicles do much more than clean up a cell’s trash—they also carry signals to distant parts of the body, where they can impact multiple dimensions of cellular life.
Exosome Basics
Exosome Basics
Clotilde Théry, Clotilde Théry | Jul 1, 2011
Exosomes are small membrane vesicles secreted by most cell types. Internal vesicles form by the inward budding of cellular compartments known as multivesicular endosomes (MVE).